TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 3nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 4nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 5nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 6nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 8nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 9nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 9nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 9nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 11nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 11nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 14nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 17nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 18nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 25nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 30nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 31nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 32nMAssay Description:Assay A: DHODH enzyme assays were performed with 6 nM recombinant human DHODH (purified essentially as described by Walse et. al., Biochemistry, 47, ...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 32nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 32nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 33nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 39nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 47nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 50nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 66nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 78nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 88nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 96nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 112nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 119nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 124nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 136nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 166nMAssay Description:Assay A: DHODH enzyme assays were performed with 6 nM recombinant human DHODH (purified essentially as described by Walse et. al., Biochemistry, 47, ...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 220nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 290nMAssay Description:Assay A: DHODH enzyme assays were performed with 6 nM recombinant human DHODH (purified essentially as described by Walse et. al., Biochemistry, 47, ...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 355nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 441nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 459nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 735nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 881nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 1.11E+3nMAssay Description:Assay A: DHODH enzyme assays were performed with 6 nM recombinant human DHODH (purified essentially as described by Walse et. al., Biochemistry, 47, ...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 2.00E+3nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 2.08E+3nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 2.17E+3nMAssay Description:Assay A: DHODH enzyme assays were performed with 6 nM recombinant human DHODH (purified essentially as described by Walse et. al., Biochemistry, 47, ...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 2.44E+3nMAssay Description:Assay A: DHODH enzyme assays were performed with 6 nM recombinant human DHODH (purified essentially as described by Walse et. al., Biochemistry, 47, ...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 2.67E+3nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: >3.00E+3nMAssay Description:Assay B: Example compounds as described herein were dispensed with an acoustic liquid handler, Echo 550 (Labcyte) to a maximum volume of 50 nl per we...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 5.83E+3nMAssay Description:Assay A: DHODH enzyme assays were performed with 6 nM recombinant human DHODH (purified essentially as described by Walse et. al., Biochemistry, 47, ...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 6.36E+3nMAssay Description:Assay A: DHODH enzyme assays were performed with 6 nM recombinant human DHODH (purified essentially as described by Walse et. al., Biochemistry, 47, ...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: 8.20E+3nMAssay Description:Assay A: DHODH enzyme assays were performed with 6 nM recombinant human DHODH (purified essentially as described by Walse et. al., Biochemistry, 47, ...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
Genase Therapeutics
US Patent
Genase Therapeutics
US Patent
Affinity DataIC50: >1.00E+4nMAssay Description:Assay A: DHODH enzyme assays were performed with 6 nM recombinant human DHODH (purified essentially as described by Walse et. al., Biochemistry, 47, ...More data for this Ligand-Target Pair