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Patent code US10894803

Compile Data Set for Download or QSAR
Found 4 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cation-independent mannose-6-phosphate receptor


(Homo sapiens (Human))
BDBM479364
PNG
(US10894803, Compound 18 of the invention M6Pn-^...)
Show SMILES NCCO[C@H]1OC(CO)[C@@H](O)[C@H](O)C1O[C@H]1OC(CCP(O)(O)=O)[C@@H](O)[C@H](O)C1O
Show InChI InChI=1S/C15H30NO13P/c16-2-3-26-15-13(11(21)9(19)7(5-17)28-15)29-14-12(22)10(20)8(18)6(27-14)1-4-30(23,24)25/h6-15,17-22H,1-5,16H2,(H2,23,24,25)/t6?,7?,8-,9-,10+,11+,12?,13?,14-,15+/m1/s1
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UniChem
US Patent
n/an/a 5.00E+3n/an/an/an/an/an/a



NANOMEDSYN; Centre National de la Recherche Scientifique; Universite de Montpellier

US Patent


Assay Description
96-Well plates (Maxisorp Nunc) are incubated overnight at 4 C. with 200 μl of PMP (pentamannose 6-phosphate) at the concentration of 200 μ...


US Patent US10894803 (2021)

More data for this
Ligand-Target Pair
Cation-independent mannose-6-phosphate receptor


(Homo sapiens (Human))
BDBM479366
PNG
(US10894803, Compound 24 of the invention M6C-alpha...)
Show SMILES NCCO[C@H]1OC(CO)[C@@H](O)[C@H](O)C1O[C@H]1OC(CCC(O)=O)[C@@H](O)[C@H](O)C1O
Show InChI InChI=1S/C16H29NO12/c17-3-4-26-16-14(12(24)10(22)7(5-18)28-16)29-15-13(25)11(23)9(21)6(27-15)1-2-8(19)20/h6-7,9-16,18,21-25H,1-5,17H2,(H,19,20)/t6?,7?,9-,10-,11+,12+,13?,14?,15-,16+/m1/s1
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US Patent
n/an/a 1.70E+4n/an/an/an/an/an/a



NANOMEDSYN; Centre National de la Recherche Scientifique; Universite de Montpellier

US Patent


Assay Description
96-Well plates (Maxisorp Nunc) are incubated overnight at 4 C. with 200 μl of PMP (pentamannose 6-phosphate) at the concentration of 200 μ...


US Patent US10894803 (2021)

More data for this
Ligand-Target Pair
Cation-independent mannose-6-phosphate receptor


(Homo sapiens (Human))
BDBM479365
PNG
(US10894803, M6Pn-Ethyl-NH2)
Show SMILES NCCO[C@H]1OC(CCP(O)(O)=O)[C@@H](O)[C@H](O)C1O
Show InChI InChI=1S/C9H20NO8P/c10-2-3-17-9-8(13)7(12)6(11)5(18-9)1-4-19(14,15)16/h5-9,11-13H,1-4,10H2,(H2,14,15,16)/t5?,6-,7+,8?,9+/m1/s1
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US Patent
n/an/a 2.90E+4n/an/an/an/an/an/a



NANOMEDSYN; Centre National de la Recherche Scientifique; Universite de Montpellier

US Patent


Assay Description
96-Well plates (Maxisorp Nunc) are incubated overnight at 4 C. with 200 μl of PMP (pentamannose 6-phosphate) at the concentration of 200 μ...


US Patent US10894803 (2021)

More data for this
Ligand-Target Pair
Cation-independent mannose-6-phosphate receptor


(Homo sapiens (Human))
BDBM479367
PNG
(US10894803, M6C-Ethyl-NH2)
Show SMILES NCCO[C@H]1OC(CCC(O)=O)[C@@H](O)[C@H](O)C1O
Show InChI InChI=1S/C10H19NO7/c11-3-4-17-10-9(16)8(15)7(14)5(18-10)1-2-6(12)13/h5,7-10,14-16H,1-4,11H2,(H,12,13)/t5?,7-,8+,9?,10+/m1/s1
PDB
MMDB

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PC cid
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UniChem
US Patent
n/an/a 9.90E+4n/an/an/an/an/an/a



NANOMEDSYN; Centre National de la Recherche Scientifique; Universite de Montpellier

US Patent


Assay Description
96-Well plates (Maxisorp Nunc) are incubated overnight at 4 C. with 200 μl of PMP (pentamannose 6-phosphate) at the concentration of 200 μ...


US Patent US10894803 (2021)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%