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Patent code US10927076

Compile Data Set for Download or QSAR
Found 96 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483500
PNG
(US10927076, Compound Table1B.5)
Show SMILES CC(C)Cc1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1CBr
Show InChI InChI=1S/C20H22BrNO2/c1-13(2)7-16-8-18(19(23)9-17(16)10-21)20(24)22-11-14-5-3-4-6-15(14)12-22/h3-6,8-9,13,23H,7,10-12H2,1-2H3
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n/an/an/a 1.53E+4n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483505
PNG
(US10927076, Compound Table1B.10)
Show SMILES CCc1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1CO
Show InChI InChI=1S/C18H19NO3/c1-2-12-7-16(17(21)8-15(12)11-20)18(22)19-9-13-5-3-4-6-14(13)10-19/h3-8,20-21H,2,9-11H2,1H3
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n/an/an/a 1.01E+3n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483505
PNG
(US10927076, Compound Table1B.10)
Show SMILES CCc1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1CO
Show InChI InChI=1S/C18H19NO3/c1-2-12-7-16(17(21)8-15(12)11-20)18(22)19-9-13-5-3-4-6-14(13)10-19/h3-8,20-21H,2,9-11H2,1H3
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n/an/an/a 1.82E+3n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483506
PNG
(US10927076, Compound Table2.NH(CH2CH3))
Show SMILES CCNc1cc(O)c(cc1C(C)C)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C20H24N2O2/c1-4-21-18-10-19(23)17(9-16(18)13(2)3)20(24)22-11-14-7-5-6-8-15(14)12-22/h5-10,13,21,23H,4,11-12H2,1-3H3
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n/an/an/a>1.00E+5n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483511
PNG
(US10927076, Compound Table2.CHO)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1C=O
Show InChI InChI=1S/C19H19NO3/c1-12(2)16-8-17(18(22)7-15(16)11-21)19(23)20-9-13-5-3-4-6-14(13)10-20/h3-8,11-12,22H,9-10H2,1-2H3
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n/an/an/a 240n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483511
PNG
(US10927076, Compound Table2.CHO)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1C=O
Show InChI InChI=1S/C19H19NO3/c1-12(2)16-8-17(18(22)7-15(16)11-21)19(23)20-9-13-5-3-4-6-14(13)10-20/h3-8,11-12,22H,9-10H2,1-2H3
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n/an/an/a 1.21E+3n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483512
PNG
(US10927076, Compound Table2.NH2)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1N
Show InChI InChI=1S/C18H20N2O2/c1-11(2)14-7-15(17(21)8-16(14)19)18(22)20-9-12-5-3-4-6-13(12)10-20/h3-8,11,21H,9-10,19H2,1-2H3
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n/an/an/a 710n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483514
PNG
(US10927076, Compound Table2.CH(OH)CH3)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1C(C)O
Show InChI InChI=1S/C20H23NO3/c1-12(2)16-8-18(19(23)9-17(16)13(3)22)20(24)21-10-14-6-4-5-7-15(14)11-21/h4-9,12-13,22-23H,10-11H2,1-3H3
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n/an/an/a 4.07E+3n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483518
PNG
(US10927076, Compound KUNB5)
Show SMILES CCCc1c(O)c(cc(C(=O)N2Cc3ccccc3C2)c1O)C(C)C
Show InChI InChI=1S/C21H25NO3/c1-4-7-16-19(23)17(13(2)3)10-18(20(16)24)21(25)22-11-14-8-5-6-9-15(14)12-22/h5-6,8-10,13,23-24H,4,7,11-12H2,1-3H3
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n/an/an/a 6.30E+3n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483521
PNG
(US10927076, Compound KUNB2)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)c(C=C)c1O
Show InChI InChI=1S/C20H21NO3/c1-4-15-18(22)16(12(2)3)9-17(19(15)23)20(24)21-10-13-7-5-6-8-14(13)11-21/h4-9,12,22-23H,1,10-11H2,2-3H3
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n/an/an/a>1.00E+5n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483523
PNG
(US10927076, Compound KUNB14)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)c(CO)c1O
Show InChI InChI=1S/C19H21NO4/c1-11(2)14-7-15(18(23)16(10-21)17(14)22)19(24)20-8-12-5-3-4-6-13(12)9-20/h3-7,11,21-23H,8-10H2,1-2H3
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n/an/an/a>1.00E+5n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483525
PNG
(US10927076, Compound KUNB22)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)c2C(=O)CCc12
Show InChI InChI=1S/C21H21NO3/c1-12(2)16-9-17(20(24)19-15(16)7-8-18(19)23)21(25)22-10-13-5-3-4-6-14(13)11-22/h3-6,9,12,24H,7-8,10-11H2,1-2H3
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n/an/an/a 110n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483526
PNG
(US10927076, Compound KUNB17)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)c2OC3NN=CC3c12
Show InChI InChI=1S/C21H21N3O3/c1-11(2)14-7-15(18(25)19-17(14)16-8-22-23-20(16)27-19)21(26)24-9-12-5-3-4-6-13(12)10-24/h3-8,11,16,20,23,25H,9-10H2,1-2H3
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n/an/an/a>1.00E+4n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483532
PNG
(US10927076, Compound KUNB24)
Show SMILES CCCC1Cc2c(C1=O)c(O)c(cc2C(C)C)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C24H27NO3/c1-4-7-15-10-19-18(14(2)3)11-20(23(27)21(19)22(15)26)24(28)25-12-16-8-5-6-9-17(16)13-25/h5-6,8-9,11,14-15,27H,4,7,10,12-13H2,1-3H3
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n/an/an/a>1.00E+5n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483534
PNG
(US10927076, Compound KUNB26)
Show SMILES CCN1Cc2c(C1=O)c(O)c(cc2C(C)C)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C22H24N2O3/c1-4-23-12-18-16(13(2)3)9-17(20(25)19(18)22(23)27)21(26)24-10-14-7-5-6-8-15(14)11-24/h5-9,13,25H,4,10-12H2,1-3H3
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n/an/an/a>1.00E+4n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483485
PNG
(US10927076, Compound Table1A.1)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1CO
Show InChI InChI=1S/C19H21NO3/c1-12(2)16-8-17(18(22)7-15(16)11-21)19(23)20-9-13-5-3-4-6-14(13)10-20/h3-8,12,21-22H,9-11H2,1-2H3
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n/an/an/a 1.97E+3n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483492
PNG
(US10927076, Compound Table1A.7)
Show SMILES CNCc1cc(O)c(cc1C(C)C)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C20H24N2O2/c1-13(2)17-9-18(19(23)8-16(17)10-21-3)20(24)22-11-14-6-4-5-7-15(14)12-22/h4-9,13,21,23H,10-12H2,1-3H3
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n/an/an/a 2.32E+4n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483495
PNG
(US10927076, Compound Table1A.10)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1CC(N)=O
Show InChI InChI=1S/C20H22N2O3/c1-12(2)16-9-17(18(23)7-15(16)8-19(21)24)20(25)22-10-13-5-3-4-6-14(13)11-22/h3-7,9,12,23H,8,10-11H2,1-2H3,(H2,21,24)
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n/an/an/a 1.52E+4n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483497
PNG
(US10927076, Compound Table1B.2)
Show SMILES OCc1cc(O)c(cc1Sc1ccccc1O)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C22H19NO4S/c24-13-16-9-19(26)17(10-21(16)28-20-8-4-3-7-18(20)25)22(27)23-11-14-5-1-2-6-15(14)12-23/h1-10,24-26H,11-13H2
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n/an/an/a 4.40E+3n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483502
PNG
(US10927076, Compound Table1B.7)
Show SMILES CCC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1CO
Show InChI InChI=1S/C20H23NO3/c1-3-13(2)17-9-18(19(23)8-16(17)12-22)20(24)21-10-14-6-4-5-7-15(14)11-21/h4-9,13,22-23H,3,10-12H2,1-2H3
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n/an/an/a 2.68E+3n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483503
PNG
(US10927076, Compound Table1B.8)
Show SMILES OCc1cc(O)c(cc1Cl)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C16H14ClNO3/c17-14-6-13(15(20)5-12(14)9-19)16(21)18-7-10-3-1-2-4-11(10)8-18/h1-6,19-20H,7-9H2
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n/an/an/a>5.00E+4n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483507
PNG
(US10927076, Compound Table2.N(CH2CH3)2)
Show SMILES CCN(CC)c1cc(O)c(cc1C(C)C)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C22H28N2O2/c1-5-23(6-2)20-12-21(25)19(11-18(20)15(3)4)22(26)24-13-16-9-7-8-10-17(16)14-24/h7-12,15,25H,5-6,13-14H2,1-4H3
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University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483509
PNG
(US10927076, Compound Table2.NH(CO)CH3)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1NC(C)=O
Show InChI InChI=1S/C20H22N2O3/c1-12(2)16-8-17(19(24)9-18(16)21-13(3)23)20(25)22-10-14-6-4-5-7-15(14)11-22/h4-9,12,24H,10-11H2,1-3H3,(H,21,23)
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University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483510
PNG
(US10927076, Compound Table2.NH(CN))
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1NC#N
Show InChI InChI=1S/C19H19N3O2/c1-12(2)15-7-16(18(23)8-17(15)21-11-20)19(24)22-9-13-5-3-4-6-14(13)10-22/h3-8,12,21,23H,9-10H2,1-2H3
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n/an/an/a 180n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483512
PNG
(US10927076, Compound Table2.NH2)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1N
Show InChI InChI=1S/C18H20N2O2/c1-11(2)14-7-15(17(21)8-16(14)19)18(22)20-9-12-5-3-4-6-13(12)10-20/h3-8,11,21H,9-10,19H2,1-2H3
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n/an/an/a 460n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483513
PNG
(US10927076, Compound Table2.C=CF2)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1C=C(F)F
Show InChI InChI=1S/C20H19F2NO2/c1-12(2)16-9-17(18(24)7-15(16)8-19(21)22)20(25)23-10-13-5-3-4-6-14(13)11-23/h3-9,12,24H,10-11H2,1-2H3
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n/an/an/a 4.21E+3n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483514
PNG
(US10927076, Compound Table2.CH(OH)CH3)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1C(C)O
Show InChI InChI=1S/C20H23NO3/c1-12(2)16-8-18(19(23)9-17(16)13(3)22)20(24)21-10-14-6-4-5-7-15(14)11-21/h4-9,12-13,22-23H,10-11H2,1-3H3
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n/an/an/a 4.87E+3n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483515
PNG
(US10927076, Compound Table2.CONH2)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1C(N)=O
Show InChI InChI=1S/C19H20N2O3/c1-11(2)14-7-16(17(22)8-15(14)18(20)23)19(24)21-9-12-5-3-4-6-13(12)10-21/h3-8,11,22H,9-10H2,1-2H3,(H2,20,23)
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n/an/an/a 370n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483519
PNG
(US10927076, Compound KUNB7)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)c(CCO)c1O
Show InChI InChI=1S/C20H23NO4/c1-12(2)16-9-17(19(24)15(7-8-22)18(16)23)20(25)21-10-13-5-3-4-6-14(13)11-21/h3-6,9,12,22-24H,7-8,10-11H2,1-2H3
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University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483520
PNG
(US10927076, Compound KUNB3)
Show SMILES CCc1c(O)c(cc(C(=O)N2Cc3ccccc3C2)c1O)C(C)C
Show InChI InChI=1S/C20H23NO3/c1-4-15-18(22)16(12(2)3)9-17(19(15)23)20(24)21-10-13-7-5-6-8-14(13)11-21/h5-9,12,22-23H,4,10-11H2,1-3H3
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n/an/an/a 3.31E+3n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483527
PNG
(US10927076, Compound KUNB18)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)c2cn[nH]c12
Show InChI InChI=1S/C19H19N3O2/c1-11(2)14-7-15(18(23)16-8-20-21-17(14)16)19(24)22-9-12-5-3-4-6-13(12)10-22/h3-8,11,23H,9-10H2,1-2H3,(H,20,21)
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n/an/an/a 3.71E+3n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483487
PNG
(US10927076, Compound Table1A.3)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1CCl
Show InChI InChI=1S/C19H20ClNO2/c1-12(2)16-8-17(18(22)7-15(16)9-20)19(23)21-10-13-5-3-4-6-14(13)11-21/h3-8,12,22H,9-11H2,1-2H3
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n/an/an/a 2.52E+4n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483489
PNG
(US10927076, Compound Table1A.5)
Show SMILES CC(C)Cc1cc(O)c(cc1C(C)C)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C22H27NO2/c1-14(2)9-18-10-21(24)20(11-19(18)15(3)4)22(25)23-12-16-7-5-6-8-17(16)13-23/h5-8,10-11,14-15,24H,9,12-13H2,1-4H3
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University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483492
PNG
(US10927076, Compound Table1A.7)
Show SMILES CNCc1cc(O)c(cc1C(C)C)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C20H24N2O2/c1-13(2)17-9-18(19(23)8-16(17)10-21-3)20(24)22-11-14-6-4-5-7-15(14)12-22/h4-9,13,21,23H,10-12H2,1-3H3
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University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483499
PNG
(US10927076, Compound Table1B.4)
Show SMILES CC(C)Cc1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1CO
Show InChI InChI=1S/C20H23NO3/c1-13(2)7-16-8-18(19(23)9-17(16)12-22)20(24)21-10-14-5-3-4-6-15(14)11-21/h3-6,8-9,13,22-23H,7,10-12H2,1-2H3
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n/an/an/a>5.00E+4n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483510
PNG
(US10927076, Compound Table2.NH(CN))
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1NC#N
Show InChI InChI=1S/C19H19N3O2/c1-12(2)15-7-16(18(23)8-17(15)21-11-20)19(24)22-9-13-5-3-4-6-14(13)10-22/h3-8,12,21,23H,9-10H2,1-2H3
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n/an/an/a 420n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483515
PNG
(US10927076, Compound Table2.CONH2)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1C(N)=O
Show InChI InChI=1S/C19H20N2O3/c1-11(2)14-7-16(17(22)8-15(14)18(20)23)19(24)21-9-12-5-3-4-6-13(12)10-21/h3-8,11,22H,9-10H2,1-2H3,(H2,20,23)
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n/an/an/a 2.30E+3n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483522
PNG
(US10927076, Compound KUNB6)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)c(CC=C)c1O
Show InChI InChI=1S/C21H23NO3/c1-4-7-16-19(23)17(13(2)3)10-18(20(16)24)21(25)22-11-14-8-5-6-9-15(14)12-22/h4-6,8-10,13,23-24H,1,7,11-12H2,2-3H3
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n/an/an/a>1.00E+5n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483529
PNG
(US10927076, Compound KUNB20)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)c2[nH]cnc12
Show InChI InChI=1S/C19H19N3O2/c1-11(2)14-7-15(18(23)17-16(14)20-10-21-17)19(24)22-8-12-5-3-4-6-13(12)9-22/h3-7,10-11,23H,8-9H2,1-2H3,(H,20,21)
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University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483529
PNG
(US10927076, Compound KUNB20)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)c2[nH]cnc12
Show InChI InChI=1S/C19H19N3O2/c1-11(2)14-7-15(18(23)17-16(14)20-10-21-17)19(24)22-8-12-5-3-4-6-13(12)9-22/h3-7,10-11,23H,8-9H2,1-2H3,(H,20,21)
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University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483532
PNG
(US10927076, Compound KUNB24)
Show SMILES CCCC1Cc2c(C1=O)c(O)c(cc2C(C)C)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C24H27NO3/c1-4-7-15-10-19-18(14(2)3)11-20(23(27)21(19)22(15)26)24(28)25-12-16-8-5-6-9-17(16)13-25/h5-6,8-9,11,14-15,27H,4,7,10,12-13H2,1-3H3
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n/an/an/a 2.70E+3n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483533
PNG
(US10927076, Compound KUNB25)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)c2C(=O)NCc12
Show InChI InChI=1S/C20H20N2O3/c1-11(2)14-7-15(18(23)17-16(14)8-21-19(17)24)20(25)22-9-12-5-3-4-6-13(12)10-22/h3-7,11,23H,8-10H2,1-2H3,(H,21,24)
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n/an/an/a 330n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483534
PNG
(US10927076, Compound KUNB26)
Show SMILES CCN1Cc2c(C1=O)c(O)c(cc2C(C)C)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C22H24N2O3/c1-4-23-12-18-16(13(2)3)9-17(20(25)19(18)22(23)27)21(26)24-10-14-7-5-6-8-15(14)11-24/h5-9,13,25H,4,10-12H2,1-3H3
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n/an/an/a 530n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483496
PNG
(US10927076, Compound Table1B.1)
Show SMILES Cc1ccc(Sc2cc(C(=O)N3Cc4ccccc4C3)c(O)cc2CO)cc1C
Show InChI InChI=1S/C24H23NO3S/c1-15-7-8-20(9-16(15)2)29-23-11-21(22(27)10-19(23)14-26)24(28)25-12-17-5-3-4-6-18(17)13-25/h3-11,26-27H,12-14H2,1-2H3
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n/an/an/a 2.86E+3n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483496
PNG
(US10927076, Compound Table1B.1)
Show SMILES Cc1ccc(Sc2cc(C(=O)N3Cc4ccccc4C3)c(O)cc2CO)cc1C
Show InChI InChI=1S/C24H23NO3S/c1-15-7-8-20(9-16(15)2)29-23-11-21(22(27)10-19(23)14-26)24(28)25-12-17-5-3-4-6-18(17)13-25/h3-11,26-27H,12-14H2,1-2H3
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n/an/an/a 3.44E+3n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483520
PNG
(US10927076, Compound KUNB3)
Show SMILES CCc1c(O)c(cc(C(=O)N2Cc3ccccc3C2)c1O)C(C)C
Show InChI InChI=1S/C20H23NO3/c1-4-15-18(22)16(12(2)3)9-17(19(15)23)20(24)21-10-13-7-5-6-8-14(13)11-21/h5-9,12,22-23H,4,10-11H2,1-3H3
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n/an/an/a>1.00E+5n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483533
PNG
(US10927076, Compound KUNB25)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)c2C(=O)NCc12
Show InChI InChI=1S/C20H20N2O3/c1-11(2)14-7-15(18(23)17-16(14)8-21-19(17)24)20(25)22-9-12-5-3-4-6-13(12)10-22/h3-7,11,23H,8-10H2,1-2H3,(H,21,24)
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n/an/an/a>1.00E+4n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483489
PNG
(US10927076, Compound Table1A.5)
Show SMILES CC(C)Cc1cc(O)c(cc1C(C)C)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C22H27NO2/c1-14(2)9-18-10-21(24)20(11-19(18)15(3)4)22(25)23-12-16-7-5-6-8-17(16)13-23/h5-8,10-11,14-15,24H,9,12-13H2,1-4H3
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n/an/an/a>1.00E+5n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483497
PNG
(US10927076, Compound Table1B.2)
Show SMILES OCc1cc(O)c(cc1Sc1ccccc1O)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C22H19NO4S/c24-13-16-9-19(26)17(10-21(16)28-20-8-4-3-7-18(20)25)22(27)23-11-14-5-1-2-6-15(14)12-23/h1-10,24-26H,11-13H2
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n/an/an/a 2.68E+3n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483498
PNG
(US10927076, Compound Table1B.3)
Show SMILES CN(c1ccccc1)c1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1CO
Show InChI InChI=1S/C23H22N2O3/c1-24(19-9-3-2-4-10-19)21-12-20(22(27)11-18(21)15-26)23(28)25-13-16-7-5-6-8-17(16)14-25/h2-12,26-27H,13-15H2,1H3
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n/an/an/a 1.50E+3n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483498
PNG
(US10927076, Compound Table1B.3)
Show SMILES CN(c1ccccc1)c1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1CO
Show InChI InChI=1S/C23H22N2O3/c1-24(19-9-3-2-4-10-19)21-12-20(22(27)11-18(21)15-26)23(28)25-13-16-7-5-6-8-17(16)14-25/h2-12,26-27H,13-15H2,1H3
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n/an/an/a 5.05E+3n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483501
PNG
(US10927076, Compound Table1B.6)
Show SMILES CCC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1CBr
Show InChI InChI=1S/C20H22BrNO2/c1-3-13(2)17-9-18(19(23)8-16(17)10-21)20(24)22-11-14-6-4-5-7-15(14)12-22/h4-9,13,23H,3,10-12H2,1-2H3
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n/an/an/a 1.79E+3n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483516
PNG
(US10927076, Compound KUNB1)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)c(C=O)c1O
Show InChI InChI=1S/C19H19NO4/c1-11(2)14-7-15(18(23)16(10-21)17(14)22)19(24)20-8-12-5-3-4-6-13(12)9-20/h3-7,10-11,22-23H,8-9H2,1-2H3
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n/an/an/a>1.00E+5n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483518
PNG
(US10927076, Compound KUNB5)
Show SMILES CCCc1c(O)c(cc(C(=O)N2Cc3ccccc3C2)c1O)C(C)C
Show InChI InChI=1S/C21H25NO3/c1-4-7-16-19(23)17(13(2)3)10-18(20(16)24)21(25)22-11-14-8-5-6-9-15(14)12-22/h5-6,8-10,13,23-24H,4,7,11-12H2,1-3H3
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n/an/an/a>7.50E+4n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483521
PNG
(US10927076, Compound KUNB2)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)c(C=C)c1O
Show InChI InChI=1S/C20H21NO3/c1-4-15-18(22)16(12(2)3)9-17(19(15)23)20(24)21-10-13-7-5-6-8-14(13)11-21/h4-9,12,22-23H,1,10-11H2,2-3H3
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n/an/an/a 5.24E+3n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483524
PNG
(US10927076, Compound KUNB31a)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)c2oncc12
Show InChI InChI=1S/C19H18N2O3/c1-11(2)14-7-15(17(22)18-16(14)8-20-24-18)19(23)21-9-12-5-3-4-6-13(12)10-21/h3-8,11,22H,9-10H2,1-2H3
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n/an/an/a 180n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483524
PNG
(US10927076, Compound KUNB31a)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)c2oncc12
Show InChI InChI=1S/C19H18N2O3/c1-11(2)14-7-15(17(22)18-16(14)8-20-24-18)19(23)21-9-12-5-3-4-6-13(12)10-21/h3-8,11,22H,9-10H2,1-2H3
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n/an/an/a 3.55E+3n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483528
PNG
(US10927076, Compound KUNB19)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)c2nc[nH]c12
Show InChI InChI=1S/C19H19N3O2/c1-11(2)14-7-15(18(23)17-16(14)20-10-21-17)19(24)22-8-12-5-3-4-6-13(12)9-22/h3-7,10-11,23H,8-9H2,1-2H3,(H,20,21)
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n/an/an/a 6.30E+3n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483530
PNG
(US10927076, Compound KUNB28)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)c2C(=O)C(C)Cc12
Show InChI InChI=1S/C22H23NO3/c1-12(2)16-9-18(21(25)19-17(16)8-13(3)20(19)24)22(26)23-10-14-6-4-5-7-15(14)11-23/h4-7,9,12-13,25H,8,10-11H2,1-3H3
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n/an/an/a 295n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483531
PNG
(US10927076, Compound KUNB23)
Show SMILES CCC1Cc2c(C1=O)c(O)c(cc2C(C)C)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C23H25NO3/c1-4-14-9-18-17(13(2)3)10-19(22(26)20(18)21(14)25)23(27)24-11-15-7-5-6-8-16(15)12-24/h5-8,10,13-14,26H,4,9,11-12H2,1-3H3
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n/an/an/a 580n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483485
PNG
(US10927076, Compound Table1A.1)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1CO
Show InChI InChI=1S/C19H21NO3/c1-12(2)16-8-17(18(22)7-15(16)11-21)19(23)20-9-13-5-3-4-6-14(13)10-20/h3-8,12,21-22H,9-11H2,1-2H3
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n/an/an/a 4.21E+3n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483488
PNG
(US10927076, Compound Table1A.4)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1CBr
Show InChI InChI=1S/C19H20BrNO2/c1-12(2)16-8-17(18(22)7-15(16)9-20)19(23)21-10-13-5-3-4-6-14(13)11-21/h3-8,12,22H,9-11H2,1-2H3
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n/an/an/a 4.98E+3n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483493
PNG
(US10927076, Compound Table1A.8)
Show SMILES COCc1cc(O)c(cc1C(C)C)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C20H23NO3/c1-13(2)17-9-18(19(22)8-16(17)12-24-3)20(23)21-10-14-6-4-5-7-15(14)11-21/h4-9,13,22H,10-12H2,1-3H3
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n/an/an/a>5.00E+4n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483499
PNG
(US10927076, Compound Table1B.4)
Show SMILES CC(C)Cc1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1CO
Show InChI InChI=1S/C20H23NO3/c1-13(2)7-16-8-18(19(23)9-17(16)12-22)20(24)21-10-14-5-3-4-6-15(14)11-21/h3-6,8-9,13,22-23H,7,10-12H2,1-2H3
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University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483500
PNG
(US10927076, Compound Table1B.5)
Show SMILES CC(C)Cc1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1CBr
Show InChI InChI=1S/C20H22BrNO2/c1-13(2)7-16-8-18(19(23)9-17(16)10-21)20(24)22-11-14-5-3-4-6-15(14)12-22/h3-6,8-9,13,23H,7,10-12H2,1-2H3
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n/an/an/a 3.79E+4n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483504
PNG
(US10927076, Compound Table1B.9)
Show SMILES OCc1cc(O)c(cc1C(F)(F)F)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C17H14F3NO3/c18-17(19,20)14-6-13(15(23)5-12(14)9-22)16(24)21-7-10-3-1-2-4-11(10)8-21/h1-6,22-23H,7-9H2
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n/an/an/a 5.40E+3n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483508
PNG
(US10927076, Compound Table2.NHCHO)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1NC=O
Show InChI InChI=1S/C19H20N2O3/c1-12(2)15-7-16(18(23)8-17(15)20-11-22)19(24)21-9-13-5-3-4-6-14(13)10-21/h3-8,11-12,23H,9-10H2,1-2H3,(H,20,22)
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n/an/an/a 7.59E+3n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483513
PNG
(US10927076, Compound Table2.C=CF2)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1C=C(F)F
Show InChI InChI=1S/C20H19F2NO2/c1-12(2)16-9-17(18(24)7-15(16)8-19(21)22)20(25)23-10-13-5-3-4-6-14(13)11-23/h3-9,12,24H,10-11H2,1-2H3
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n/an/an/a 5.18E+3n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483525
PNG
(US10927076, Compound KUNB22)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)c2C(=O)CCc12
Show InChI InChI=1S/C21H21NO3/c1-12(2)16-9-17(20(24)19-15(16)7-8-18(19)23)21(25)22-10-13-5-3-4-6-14(13)11-22/h3-6,9,12,24H,7-8,10-11H2,1-2H3
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n/an/an/a 9.30E+3n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483527
PNG
(US10927076, Compound KUNB18)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)c2cn[nH]c12
Show InChI InChI=1S/C19H19N3O2/c1-11(2)14-7-15(18(23)16-8-20-21-17(14)16)19(24)22-9-12-5-3-4-6-13(12)10-22/h3-8,11,23H,9-10H2,1-2H3,(H,20,21)
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n/an/an/a 8.25E+4n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483530
PNG
(US10927076, Compound KUNB28)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)c2C(=O)C(C)Cc12
Show InChI InChI=1S/C22H23NO3/c1-12(2)16-9-18(21(25)19-17(16)8-13(3)20(19)24)22(26)23-10-14-6-4-5-7-15(14)11-23/h4-7,9,12-13,25H,8,10-11H2,1-3H3
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n/an/an/a>1.00E+4n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483531
PNG
(US10927076, Compound KUNB23)
Show SMILES CCC1Cc2c(C1=O)c(O)c(cc2C(C)C)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C23H25NO3/c1-4-14-9-18-17(13(2)3)10-19(22(26)20(18)21(14)25)23(27)24-11-15-7-5-6-8-16(15)12-24/h5-8,10,13-14,26H,4,9,11-12H2,1-3H3
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n/an/an/a>1.00E+4n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483486
PNG
(US10927076, Compound Table1A.2)
Show SMILES CCc1cc(O)c(cc1C(C)C)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C20H23NO2/c1-4-14-9-19(22)18(10-17(14)13(2)3)20(23)21-11-15-7-5-6-8-16(15)12-21/h5-10,13,22H,4,11-12H2,1-3H3
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n/an/an/a>5.00E+4n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483487
PNG
(US10927076, Compound Table1A.3)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1CCl
Show InChI InChI=1S/C19H20ClNO2/c1-12(2)16-8-17(18(22)7-15(16)9-20)19(23)21-10-13-5-3-4-6-14(13)11-21/h3-8,12,22H,9-11H2,1-2H3
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n/an/an/a>1.00E+5n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483488
PNG
(US10927076, Compound Table1A.4)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1CBr
Show InChI InChI=1S/C19H20BrNO2/c1-12(2)16-8-17(18(22)7-15(16)9-20)19(23)21-10-13-5-3-4-6-14(13)11-21/h3-8,12,22H,9-11H2,1-2H3
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n/an/an/a 730n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483494
PNG
(US10927076, Compound Table1A.9)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1CC#N
Show InChI InChI=1S/C20H20N2O2/c1-13(2)17-10-18(19(23)9-14(17)7-8-21)20(24)22-11-15-5-3-4-6-16(15)12-22/h3-6,9-10,13,23H,7,11-12H2,1-2H3
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n/an/an/a 2.28E+3n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483495
PNG
(US10927076, Compound Table1A.10)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1CC(N)=O
Show InChI InChI=1S/C20H22N2O3/c1-12(2)16-9-17(18(23)7-15(16)8-19(21)24)20(25)22-10-13-5-3-4-6-14(13)11-22/h3-7,9,12,23H,8,10-11H2,1-2H3,(H2,21,24)
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n/an/an/a 5.50E+3n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483502
PNG
(US10927076, Compound Table1B.7)
Show SMILES CCC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1CO
Show InChI InChI=1S/C20H23NO3/c1-3-13(2)17-9-18(19(23)8-16(17)12-22)20(24)21-10-14-6-4-5-7-15(14)11-21/h4-9,13,22-23H,3,10-12H2,1-2H3
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n/an/an/a 4.40E+3n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483504
PNG
(US10927076, Compound Table1B.9)
Show SMILES OCc1cc(O)c(cc1C(F)(F)F)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C17H14F3NO3/c18-17(19,20)14-6-13(15(23)5-12(14)9-22)16(24)21-7-10-3-1-2-4-11(10)8-21/h1-6,22-23H,7-9H2
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n/an/an/a 6.35E+3n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483506
PNG
(US10927076, Compound Table2.NH(CH2CH3))
Show SMILES CCNc1cc(O)c(cc1C(C)C)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C20H24N2O2/c1-4-21-18-10-19(23)17(9-16(18)13(2)3)20(24)22-11-14-7-5-6-8-15(14)12-22/h5-10,13,21,23H,4,11-12H2,1-3H3
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n/an/an/a>1.00E+5n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483508
PNG
(US10927076, Compound Table2.NHCHO)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1NC=O
Show InChI InChI=1S/C19H20N2O3/c1-12(2)15-7-16(18(23)8-17(15)20-11-22)19(24)21-9-13-5-3-4-6-14(13)10-21/h3-8,11-12,23H,9-10H2,1-2H3,(H,20,22)
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n/an/an/a 3.02E+4n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483517
PNG
(US10927076, Compound KUNB4)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)c(C(C)N)c1O
Show InChI InChI=1S/C20H24N2O3/c1-11(2)15-8-16(19(24)17(12(3)21)18(15)23)20(25)22-9-13-6-4-5-7-14(13)10-22/h4-8,11-12,23-24H,9-10,21H2,1-3H3
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n/an/an/a>1.00E+5n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483522
PNG
(US10927076, Compound KUNB6)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)c(CC=C)c1O
Show InChI InChI=1S/C21H23NO3/c1-4-7-16-19(23)17(13(2)3)10-18(20(16)24)21(25)22-11-14-8-5-6-9-15(14)12-22/h4-6,8-10,13,23-24H,1,7,11-12H2,2-3H3
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n/an/an/a>1.00E+5n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483486
PNG
(US10927076, Compound Table1A.2)
Show SMILES CCc1cc(O)c(cc1C(C)C)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C20H23NO2/c1-4-14-9-19(22)18(10-17(14)13(2)3)20(23)21-11-15-7-5-6-8-16(15)12-21/h5-10,13,22H,4,11-12H2,1-3H3
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n/an/an/a>5.00E+4n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483493
PNG
(US10927076, Compound Table1A.8)
Show SMILES COCc1cc(O)c(cc1C(C)C)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C20H23NO3/c1-13(2)17-9-18(19(22)8-16(17)12-24-3)20(23)21-10-14-6-4-5-7-15(14)11-21/h4-9,13,22H,10-12H2,1-3H3
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n/an/an/a>5.00E+4n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483494
PNG
(US10927076, Compound Table1A.9)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1CC#N
Show InChI InChI=1S/C20H20N2O2/c1-13(2)17-10-18(19(23)9-14(17)7-8-21)20(24)22-11-15-5-3-4-6-16(15)12-22/h3-6,9-10,13,23H,7,11-12H2,1-2H3
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n/an/an/a 970n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483501
PNG
(US10927076, Compound Table1B.6)
Show SMILES CCC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1CBr
Show InChI InChI=1S/C20H22BrNO2/c1-3-13(2)17-9-18(19(23)8-16(17)10-21)20(24)22-11-14-6-4-5-7-15(14)12-22/h4-9,13,23H,3,10-12H2,1-2H3
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n/an/an/a 5.88E+3n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483503
PNG
(US10927076, Compound Table1B.8)
Show SMILES OCc1cc(O)c(cc1Cl)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C16H14ClNO3/c17-14-6-13(15(20)5-12(14)9-19)16(21)18-7-10-3-1-2-4-11(10)8-18/h1-6,19-20H,7-9H2
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n/an/an/a>5.00E+4n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483507
PNG
(US10927076, Compound Table2.N(CH2CH3)2)
Show SMILES CCN(CC)c1cc(O)c(cc1C(C)C)C(=O)N1Cc2ccccc2C1
Show InChI InChI=1S/C22H28N2O2/c1-5-23(6-2)20-12-21(25)19(11-18(20)15(3)4)22(26)24-13-16-9-7-8-10-17(16)14-24/h7-12,15,25H,5-6,13-14H2,1-4H3
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n/an/an/a>1.00E+5n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483509
PNG
(US10927076, Compound Table2.NH(CO)CH3)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)cc1NC(C)=O
Show InChI InChI=1S/C20H22N2O3/c1-12(2)16-8-17(19(24)9-18(16)21-13(3)23)20(25)22-10-14-6-4-5-7-15(14)11-22/h4-9,12,24H,10-11H2,1-3H3,(H,21,23)
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n/an/an/a>1.00E+5n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483516
PNG
(US10927076, Compound KUNB1)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)c(C=O)c1O
Show InChI InChI=1S/C19H19NO4/c1-11(2)14-7-15(18(23)16(10-21)17(14)22)19(24)20-8-12-5-3-4-6-13(12)9-20/h3-7,10-11,22-23H,8-9H2,1-2H3
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n/an/an/a>1.00E+5n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483517
PNG
(US10927076, Compound KUNB4)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)c(C(C)N)c1O
Show InChI InChI=1S/C20H24N2O3/c1-11(2)15-8-16(19(24)17(12(3)21)18(15)23)20(25)22-9-13-6-4-5-7-14(13)10-22/h4-8,11-12,23-24H,9-10,21H2,1-3H3
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n/an/an/a>1.00E+5n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483519
PNG
(US10927076, Compound KUNB7)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)c(CCO)c1O
Show InChI InChI=1S/C20H23NO4/c1-12(2)16-9-17(19(24)15(7-8-22)18(16)23)20(25)21-10-13-5-3-4-6-14(13)11-21/h3-6,9,12,22-24H,7-8,10-11H2,1-2H3
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n/an/an/a>1.00E+5n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483523
PNG
(US10927076, Compound KUNB14)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)c(CO)c1O
Show InChI InChI=1S/C19H21NO4/c1-11(2)14-7-15(18(23)16(10-21)17(14)22)19(24)20-8-12-5-3-4-6-13(12)9-20/h3-7,11,21-23H,8-10H2,1-2H3
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n/an/an/a 4.27E+3n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Heat shock protein HSP 90-beta


(Homo sapiens (Human))
BDBM483526
PNG
(US10927076, Compound KUNB17)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)c2OC3NN=CC3c12
Show InChI InChI=1S/C21H21N3O3/c1-11(2)14-7-15(18(25)19-17(14)16-8-22-23-20(16)27-19)21(26)24-9-12-5-3-4-6-13(12)10-24/h3-8,11,16,20,23,25H,9-10H2,1-2H3
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n/an/an/a 720n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))
BDBM483528
PNG
(US10927076, Compound KUNB19)
Show SMILES CC(C)c1cc(C(=O)N2Cc3ccccc3C2)c(O)c2nc[nH]c12
Show InChI InChI=1S/C19H19N3O2/c1-11(2)14-7-15(18(23)17-16(14)20-10-21-17)19(24)22-8-12-5-3-4-6-13(12)9-22/h3-7,10-11,23H,8-9H2,1-2H3,(H,20,21)
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n/an/an/a>1.00E+5n/an/an/an/an/a



University of Kansas

US Patent


Assay Description
Assay was performed in 96-well format in black, flat bottom plates (Santa Cruz Biotechnology) with a final volume of 100 μL. 25 μL of assay...


US Patent US10927076 (2021)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%