BindingDB logo
myBDB logout

Patent code US10927110

Compile Data Set for Download or QSAR
Found 31 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM483949
PNG
((S)-3-(5-(3-cyanophenyl)-3H-imidazo[4,5-b]pyridin-...)
Show SMILES F[C@@]1(CCCN(C1)C#N)c1nc2ccc(nc2[nH]1)-c1cccc(c1)C#N
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 55n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10927110 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM483942
PNG
((R)-3-(5-([1,1′-biphenyl]-3-yl)-1,3,4-oxadia...)
Show SMILES F[C@@]1(CCCN(C1)C#N)c1nnc(o1)-c1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C20H17FN4O/c21-20(10-5-11-25(13-20)14-22)19-24-23-18(26-19)17-9-4-8-16(12-17)15-6-2-1-3-7-15/h1-4,6-9,12H,5,10-11,13H2/t20-/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 55n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10927110 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM483958
PNG
((R)-4-(2-(1-cyano-3-fluoropiperidin-3-yl)benzo[d]o...)
Show SMILES F[C@@]1(CCCN(C1)C#N)c1nc2cc(ccc2o1)-c1ccnc(c1)C#N
Show InChI InChI=1S/C19H14FN5O/c20-19(5-1-7-25(11-19)12-22)18-24-16-9-13(2-3-17(16)26-18)14-4-6-23-15(8-14)10-21/h2-4,6,8-9H,1,5,7,11H2/t19-/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 55n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10927110 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM483955
PNG
((R)-3-(5-(3-cyanophenyl)benzo[d]oxazol-2-yl)-3-flu...)
Show SMILES FC1(CCCN(C1)C#N)c1nc2cc(ccc2o1)-c1cccc(c1)C#N
Show InChI InChI=1S/C20H15FN4O/c21-20(7-2-8-25(12-20)13-23)19-24-17-10-16(5-6-18(17)26-19)15-4-1-3-14(9-15)11-22/h1,3-6,9-10H,2,7-8,12H2
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 55n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10927110 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM483963
PNG
((R)-4-(2-(1-cyano-3-fluoropiperidin-3-yl)oxazolo[5...)
Show SMILES F[C@@]1(CCCN(C1)C#N)c1nc2cc(cnc2o1)-c1ccnc(c1)C#N
Show InChI InChI=1S/C18H13FN6O/c19-18(3-1-5-25(10-18)11-21)17-24-15-7-13(9-23-16(15)26-17)12-2-4-22-14(6-12)8-20/h2,4,6-7,9H,1,3,5,10H2/t18-/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10927110 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM483953
PNG
(3-(6-(3-cyanophenyl)-1H-imidazo[4,5-b]pyridin-2-yl...)
Show SMILES FC1(CCCN(C1)C#N)c1nc2ccc(nc2[nH]1)-c1cccc(c1)C#N
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10927110 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM483951
PNG
((R)-4-(2-(1-cyano-3-fluoropiperidin-3-yl)-3H-imida...)
Show SMILES F[C@@]1(CCCN(C1)C#N)c1nc2ncc(cc2[nH]1)-c1ccnc(c1)C#N
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10927110 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM483944
PNG
((R)-4-(5-(1-cyano-3-fluoropiperidin-3-yl)-1,3,4-ox...)
Show SMILES F[C@@]1(CCCN(C1)C#N)c1nnc(o1)-c1ccnc(c1)-c1ccnc(c1)C#N
Show InChI InChI=1S/C19H14FN7O/c20-19(4-1-7-27(11-19)12-22)18-26-25-17(28-18)14-3-6-24-16(9-14)13-2-5-23-15(8-13)10-21/h2-3,5-6,8-9H,1,4,7,11H2/t19-/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10927110 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM483943
PNG
(3-(5-([1,1′-biphenyl]-4-yl)-1,3,4-oxadiazol-...)
Show SMILES FC1(CCCN(C1)C#N)c1nnc(o1)-c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C20H17FN4O/c21-20(11-4-12-25(13-20)14-22)19-24-23-18(26-19)17-9-7-16(8-10-17)15-5-2-1-3-6-15/h1-3,5-10H,4,11-13H2
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10927110 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM483952
PNG
((R)-4-(2-(1-cyano-3-fluoropiperidin-3-yl)-1H-imida...)
Show SMILES F[C@@]1(CCCN(C1)C#N)c1nc2ccc(nc2[nH]1)-c1ccnc(c1)C#N
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10927110 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM483961
PNG
(3-(6-(3-cyanophenyl)oxazolo[5,4-b]pyridin-2-yl)-3-...)
Show SMILES FC1(CCCN(C1)C#N)c1nc2cc(cnc2o1)-c1cccc(c1)C#N
Show InChI InChI=1S/C19H14FN5O/c20-19(5-2-6-25(11-19)12-22)18-24-16-8-15(10-23-17(16)26-18)14-4-1-3-13(7-14)9-21/h1,3-4,7-8,10H,2,5-6,11H2
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10927110 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM483948
PNG
((R)-3-fluoro-3-(5-phenyl-3H-imidazo[4,5-b]pyridin-...)
Show SMILES F[C@@]1(CCCN(C1)C#N)c1nc2ccc(nc2[nH]1)-c1ccccc1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10927110 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM483964
PNG
((R)-4-(2-(1-cyano-3-fluoropiperidin-3-yl)imidazo[1...)
Show SMILES F[C@@]1(CCCN(C1)C#N)c1cn2ccc(cc2n1)-c1ccnc(c1)C#N
Show InChI InChI=1S/C19H15FN6/c20-19(4-1-6-25(12-19)13-22)17-11-26-7-3-15(9-18(26)24-17)14-2-5-23-16(8-14)10-21/h2-3,5,7-9,11H,1,4,6,12H2/t19-/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10927110 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM483960
PNG
((R)-4-(2-(1-cyano-3-fluoropiperidin-3-yl)benzo[d]o...)
Show SMILES F[C@@]1(CCCN(C1)C#N)c1nc2ccc(cc2o1)-c1ccnc(c1)C#N
Show InChI InChI=1S/C19H14FN5O/c20-19(5-1-7-25(11-19)12-22)18-24-16-3-2-13(9-17(16)26-18)14-4-6-23-15(8-14)10-21/h2-4,6,8-9H,1,5,7,11H2/t19-/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10927110 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM483956
PNG
((R)-6-(2-(1-cyano-3-fluoropiperidin-3-yl)benzo[d]o...)
Show SMILES F[C@@]1(CCCN(C1)C#N)c1nc2cc(ccc2o1)-c1cc(ncn1)C#N
Show InChI InChI=1S/C18H13FN6O/c19-18(4-1-5-25(9-18)10-21)17-24-15-6-12(2-3-16(15)26-17)14-7-13(8-20)22-11-23-14/h2-3,6-7,11H,1,4-5,9H2/t18-/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10927110 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM483959
PNG
((R)-2-(2-(1-cyano-3-fluoropiperidin-3-yl)benzo[d]o...)
Show SMILES F[C@@]1(CCCN(C1)C#N)c1nc2cc(ccc2o1)-c1cc(ccn1)C#N
Show InChI InChI=1S/C19H14FN5O/c20-19(5-1-7-25(11-19)12-22)18-24-16-9-14(2-3-17(16)26-18)15-8-13(10-21)4-6-23-15/h2-4,6,8-9H,1,5,7,11H2/t19-/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10927110 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM483957
PNG
((R)-2-(2-(1-cyano-3-fluoropiperidin-3-yl)benzo[d]o...)
Show SMILES F[C@@]1(CCCN(C1)C#N)c1nc2cc(ccc2o1)-c1nccc(n1)C#N
Show InChI InChI=1S/C18H13FN6O/c19-18(5-1-7-25(10-18)11-21)17-24-14-8-12(2-3-15(14)26-17)16-22-6-4-13(9-20)23-16/h2-4,6,8H,1,5,7,10H2/t18-/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10927110 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM483962
PNG
(3-(6-(3-cyanophenyl)oxazolo[4,5-b]pyridin-2-yl)-3-...)
Show SMILES FC1(CCCN(C1)C#N)c1nc2ncc(cc2o1)-c1cccc(c1)C#N
Show InChI InChI=1S/C19H14FN5O/c20-19(5-2-6-25(11-19)12-22)18-24-17-16(26-18)8-15(10-23-17)14-4-1-3-13(7-14)9-21/h1,3-4,7-8,10H,2,5-6,11H2
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 550n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10927110 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM483954
PNG
((R)-6-(2-(1-cyano-3-fluoropiperidin-3-yl)-3H-imida...)
Show SMILES F[C@@]1(CCCN(C1)C#N)c1nc2ccc(nc2[nH]1)-c1cccc(n1)C#N
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10927110 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM483945
PNG
((R)-4-(5-(1-cyano-3-fluoropiperidin-3-yl)-1,3,4-ox...)
Show SMILES F[C@@]1(CCCN(C1)C#N)c1nnc(o1)-c1ccnc(c1)C#N
Show InChI InChI=1S/C14H11FN6O/c15-14(3-1-5-21(8-14)9-17)13-20-19-12(22-13)10-2-4-18-11(6-10)7-16/h2,4,6H,1,3,5,8H2/t14-/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10927110 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM483947
PNG
(3-(6-(H-pyrazol-5-yl)-1H-benzo[d]imidazol-2-yl)-3-...)
Show SMILES FC1(CCCN(C1)C#N)c1nc2ccc(cc2[nH]1)-c1ccn[nH]1
Show InChI InChI=1S/C16H13FN6/c17-16(5-1-7-23(9-16)10-18)15-20-13-3-2-11(8-14(13)21-15)12-4-6-19-22-12/h2-4,6,8H,1,5,7,9H2/b12-11-
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10927110 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM483946
PNG
((R)-2′-(5-(1-cyano-3-fluoropiperidin-3-yl)-1...)
Show SMILES F[C@@]1(CCCN(C1)C#N)c1nnc(o1)-c1cc(ccn1)-c1ccnc(c1)C#N
Show InChI InChI=1S/C19H14FN7O/c20-19(4-1-7-27(11-19)12-22)18-26-25-17(28-18)16-9-14(3-6-24-16)13-2-5-23-15(8-13)10-21/h2-3,5-6,8-9H,1,4,7,11H2/t19-/m1/s1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10927110 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM483939
PNG
(2-(3-([1,1′-Biphenyl]-3-yl)-H-1,2,4-triazol-...)
Show SMILES N#CN1CCOC(C1)c1nc(n[nH]1)-c1cccc(c1)-c1ccccc1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10927110 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM483950
PNG
(3-(5-(1H-pyrazol-5-yl)-3H-imidazo[4,5-b]pyridin-2-...)
Show SMILES FC1(CCCN(C1)C#N)c1nc2ccc(nc2[nH]1)-c1ccn[nH]1
Show InChI InChI=1S/C15H12FN7/c16-15(5-1-7-23(8-15)9-17)14-20-12-3-2-10(19-13(12)21-14)11-4-6-18-22-11/h2-4,6H,1,5,7-8H2/b11-10-
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 5.50E+3n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10927110 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM483938
PNG
(2-(4-(3-Cyanophenyl)-1H-benzo[d]imidazol-2-yl)morp...)
Show SMILES N#CN1CCOC(C1)c1nc2c(cccc2[nH]1)-c1cccc(c1)C#N
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+4n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10927110 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM483935
PNG
(2-(6-Phenyl-3H-imidazo[4,5-b]pyridin-2-yl)morpholi...)
Show SMILES Brc1cnc2[nH]c(nc2c1)C1CCCN(C1)C#N
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+4n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10927110 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM483937
PNG
(2-(4-Phenyl-1H-benzo[d]imidazol-2-yl)morpholine-4-...)
Show SMILES O=C(Nc1ccccc1-c1ccccc1)C1CN(CCO1)C#N
Show InChI InChI=1S/C18H17N3O2/c19-13-21-10-11-23-17(12-21)18(22)20-16-9-5-4-8-15(16)14-6-2-1-3-7-14/h1-9,17H,10-12H2,(H,20,22)
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+4n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10927110 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM483941
PNG
(3-(4-([1,1′-Biphenyl]-3-yl)oxazol-2-yl)piper...)
Show SMILES N#CN1CCCC(C1)c1nc(co1)-c1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C21H19N3O/c22-15-24-11-5-10-19(13-24)21-23-20(14-25-21)18-9-4-8-17(12-18)16-6-2-1-3-7-16/h1-4,6-9,12,14,19H,5,10-11,13H2
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+4n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10927110 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM483934
PNG
(3-(6-Phenyl-3H-imidazo[4,5-b]pyridin-2-yl)piperidi...)
Show SMILES N#CN1CCCC(C1)c1nc2cc(cnc2[nH]1)-c1ccccc1
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+4n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10927110 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM483936
PNG
(3-(4-(3-Cyanophenyl)-1H-benzo[d]imidazol-2-yl)pipe...)
Show SMILES N#CN1CCCC(C1)c1nc2c(cccc2[nH]1)-c1cccc(c1)C#N
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+4n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10927110 (2021)

More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 30


(Homo sapiens (Human))
BDBM483940
PNG
(3-(4-(2-Phenoxyphenyl)oxazol-2-yl)piperidine-1-car...)
Show SMILES N#CN1CCCC(C1)c1nc(co1)-c1ccccc1Oc1ccccc1
Show InChI InChI=1S/C21H19N3O2/c22-15-24-12-6-7-16(13-24)21-23-19(14-25-21)18-10-4-5-11-20(18)26-17-8-2-1-3-9-17/h1-5,8-11,14,16H,6-7,12-13H2
PDB

Reactome pathway

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a>1.00E+4n/an/an/an/an/an/a



MISSION THERAPEUTICS LIMITED

US Patent


Assay Description
Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...


US Patent US10927110 (2021)

More data for this
Ligand-Target Pair
* indicates data uncertainty>20%