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Found 31 Enz. Inhib. hit(s) with all data for entry = 9744
TargetFascin(Homo sapiens (human))
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350103((Z)-N-(2,3-diphenyl-1,2,4- thiadiazol-5(2H)- ylide...)
Affinity DataIC50:  500nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350104(N-methyl-2,3-diphenyl- 1,2,4-thiadiazolium-5- amin...)
Affinity DataIC50:  500nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350111(N-(3-(1H-1,2,4-triazol-3- ylthio)-4- hydroxynaphth...)
Affinity DataIC50:  539nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350102(2-chloro-N-(6- chlorobenzo[d]thiazol-2- yl)-5- nit...)
Affinity DataIC50:  652nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350107(N-(3-(1H-1,2,4-triazol-3- ylthio)-4- hydroxynaphth...)
Affinity DataIC50:  683nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350100(5-(3,4-dichlorobenzyl)-1- (S,S,-dioxo- tetrahydrot...)
Affinity DataIC50:  734nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
TargetFascin(Homo sapiens (human))
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350109(N-(3-(1H-1,2,4-triazol-3- ylthio)-4- hydroxynaphth...)
Affinity DataIC50:  807nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350110(N-(3-(1H-1,2,4-triazol-3- ylthio)-4- hydroxynaphth...)
Affinity DataIC50:  890nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350120(5-(3-chlorobenzyl)-1-(2- hydroxyethyl)-1H- pyrazol...)
Affinity DataIC50:  1.20E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350108(N-(3-(1H-1,2,4-triazol-3- ylthio)-4- hydroxynaphth...)
Affinity DataIC50:  1.47E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350106(N-phenyl-2,3-diphenyl- 1,2,4-thiadiazolium-5- amin...)
Affinity DataIC50:  2.00E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350101(N-(1-(4- (trifluoromethyl)benzyl)- 1H-indazol-3-yl...)
Affinity DataIC50:  2.00E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350112((Z)-N-(3-(1H-1,2,4-triazol- 3-ylthio)-4-oxonaphtha...)
Affinity DataIC50:  2.00E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350128(5-(3,4-dichlorobenzyl)-1- o-tolyl-1H-pyrazolo[3,4-...)
Affinity DataIC50:  2.00E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350118(N-(6- chlorobenzo[d]thiazol-2- yl)acetamide | US10...)
Affinity DataIC50:  2.00E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350130(5-(3,4-dichlorobenzyl)-1- (2,4-dimethylphenyl)-1H-...)
Affinity DataIC50:  2.10E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350129(5-(3,4-dichlorobenzyl)-1- (2,3-dimethylphenyl)-1H-...)
Affinity DataIC50:  2.30E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Novita Pharmaceuticals

US Patent
LigandPNGBDBM50076451(CHEMBL3235887 | US10208043, # 14 | US10941146, # 1...)
Affinity DataIC50:  2.62E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350114(N-(3-(1H-1,2,4-triazol-3- ylthio)-4- hydroxynaphth...)
Affinity DataIC50:  2.70E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350121(2-(4-oxo-1-(S,S,-dioxo- tetrahydrothiophen-3-yl)- ...)
Affinity DataIC50:  3.40E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350127(5-(2-(benzo[d][1,3]dioxol- 5-yl)-2-oxoethyl)-1-(S,...)
Affinity DataIC50:  3.70E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350115(3-chloro-N-(6- phenoxybenzo[d]thiazol-2- yl)benzen...)
Affinity DataIC50:  4.00E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350116(N-(6- fluorobenzo[d]thiazol-2- yl)-3-nitro- benzen...)
Affinity DataIC50:  4.00E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350119(N-(benzo[d]thiazol-2- yl)cinnamamide | US10208043,...)
Affinity DataIC50:  4.00E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350122(N-(4-fluorobenzyl)-2-(4- oxo-1-(S,S-dioxo- tetrahy...)
Affinity DataIC50:  4.30E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Novita Pharmaceuticals

US Patent
LigandPNGBDBM485822(N-(4-chlorophenyl)-2-(4- oxo-1-(S,S-dioxo- tetrahy...)
Affinity DataIC50:  4.30E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350123(N-(benzo[d][1,3]dioxol-5- ylmethyl)-2-(4-oxo-1-(S,...)
Affinity DataIC50:  4.60E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350126(5-(2-(2,4-dimethylphenyl)- 2-oxoethyl)-1-(S,S-diox...)
Affinity DataIC50:  4.70E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350105(N-benzyl-2,3-diphenyl- 1,2,4-thiadiazolium-5- amin...)
Affinity DataIC50:  5.00E+3nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350125(5-(2-(2,3- dihydrobenzo[b][1,4]dioxin- 6-yl)-2-oxo...)
Affinity DataIC50:  1.00E+4nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFascin(Homo sapiens (human))
Novita Pharmaceuticals

US Patent
LigandPNGBDBM350117(2,3-dichloro-N-(6- fluorobenzo[d]thiazol-2- yl)ben...)
Affinity DataIC50:  1.30E+4nMAssay Description:A high throughput assay was developed to screen for fascin specific inhibitors. Purified polymerized F-actin with or without fascin were mixed and in...More data for this Ligand-Target Pair
In DepthDetails US Patent