Compile Data Set for Download or QSAR
maximum 50k data
Found 22 Enz. Inhib. hit(s) with all data for entry = 9750
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM485824(US10946017, Compound 23)
Affinity DataIC50:  3nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM485818(US10946017, Compound 20)
Affinity DataIC50:  10nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM485844(US10946017, Compound 11DC50:)
Affinity DataIC50:  12nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM485821(US10946017, Compound 21)
Affinity DataIC50:  29nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM485830(US10946017, Compound 27)
Affinity DataIC50:  48nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM485831(US10946017, Compound 28)
Affinity DataIC50:  65nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM485827(US10946017, Compound 25)
Affinity DataIC50:  92nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM485828(US10946017, Compound 26)
Affinity DataIC50:  121nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM485825(US10946017, Compound 24)
Affinity DataIC50:  282nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM485823(US10946017, Compound 22)
Affinity DataIC50:  544nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM485817(US10946017, Compound 19)
Affinity DataIC50: >1.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM485844(US10946017, Compound 11DC50:)
Affinity DataKd:  4.60nMAssay Description:In vitro degradation assay protocol for compounds 3-33: Panc02.13 cells were purchased from ATCC and cultured in RPMI-1640 (Gibco), supplemented with...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM485831(US10946017, Compound 28)
Affinity DataKd:  245nMAssay Description:In vitro degradation assay protocol for compounds 3-33: Panc02.13 cells were purchased from ATCC and cultured in RPMI-1640 (Gibco), supplemented with...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM485830(US10946017, Compound 27)
Affinity DataKd:  130nMAssay Description:In vitro degradation assay protocol for compounds 3-33: Panc02.13 cells were purchased from ATCC and cultured in RPMI-1640 (Gibco), supplemented with...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM485828(US10946017, Compound 26)
Affinity DataKd:  275nMAssay Description:In vitro degradation assay protocol for compounds 3-33: Panc02.13 cells were purchased from ATCC and cultured in RPMI-1640 (Gibco), supplemented with...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM485827(US10946017, Compound 25)
Affinity DataKd:  270nMAssay Description:In vitro degradation assay protocol for compounds 3-33: Panc02.13 cells were purchased from ATCC and cultured in RPMI-1640 (Gibco), supplemented with...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM485824(US10946017, Compound 23)
Affinity DataKd:  4nMAssay Description:In vitro degradation assay protocol for compounds 3-33: Panc02.13 cells were purchased from ATCC and cultured in RPMI-1640 (Gibco), supplemented with...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM485823(US10946017, Compound 22)
Affinity DataKd:  1.04E+3nMAssay Description:In vitro degradation assay protocol for compounds 3-33: Panc02.13 cells were purchased from ATCC and cultured in RPMI-1640 (Gibco), supplemented with...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM485821(US10946017, Compound 21)
Affinity DataKd:  13nMAssay Description:In vitro degradation assay protocol for compounds 3-33: Panc02.13 cells were purchased from ATCC and cultured in RPMI-1640 (Gibco), supplemented with...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM485818(US10946017, Compound 20)
Affinity DataKd:  10.4nMAssay Description:In vitro degradation assay protocol for compounds 3-33: Panc02.13 cells were purchased from ATCC and cultured in RPMI-1640 (Gibco), supplemented with...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM485817(US10946017, Compound 19)
Affinity DataKd:  725nMAssay Description:In vitro degradation assay protocol for compounds 3-33: Panc02.13 cells were purchased from ATCC and cultured in RPMI-1640 (Gibco), supplemented with...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase TBK1(Homo sapiens (Human))
Arvinas Operations

US Patent
LigandPNGBDBM485825(US10946017, Compound 24)
Affinity DataKd:  104nMAssay Description:In vitro degradation assay protocol for compounds 3-33: Panc02.13 cells were purchased from ATCC and cultured in RPMI-1640 (Gibco), supplemented with...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent