Compile Data Set for Download or QSAR
maximum 50k data
Found 14 Enz. Inhib. hit(s) with all data for entry = 7544
LigandPNGBDBM200638(US9227977, Compound (I))
Affinity DataIC50:  2.5nMAssay Description:The PI3K enzymes catalyse the phosphorylation of phosphatidylinositol 4,5-biphosphate (PIP2) to phosphatidylinositol 3,4,5-triphosphate (PIP3) in the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM200640(US9227977, Example 50)
Affinity DataIC50:  5.70nMAssay Description:The PI3K enzymes catalyse the phosphorylation of phosphatidylinositol 4,5-biphosphate (PIP2) to phosphatidylinositol 3,4,5-triphosphate (PIP3) in the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM200639(US9227977, Compound A)
Affinity DataIC50:  12nMAssay Description:The PI3K enzymes catalyse the phosphorylation of phosphatidylinositol 4,5-biphosphate (PIP2) to phosphatidylinositol 3,4,5-triphosphate (PIP3) in the...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM200637(US9227977, Compound (Ia))
Affinity DataIC50:  17nMAssay Description:As a means of assessing PI3K δ activation in response to stimuli, the phosphorylation status of the protein, Akt, a downstream product of PI3K&#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM200639(US9227977, Compound A)
Affinity DataIC50:  25nMAssay Description:The PI3K enzymes catalyse the phosphorylation of phosphatidylinositol 4,5-biphosphate (PIP2) to phosphatidylinositol 3,4,5-triphosphate (PIP3) in the...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM200638(US9227977, Compound (I))
Affinity DataIC50:  28nMAssay Description:The PI3K enzymes catalyse the phosphorylation of phosphatidylinositol 4,5-biphosphate (PIP2) to phosphatidylinositol 3,4,5-triphosphate (PIP3) in the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM200640(US9227977, Example 50)
Affinity DataIC50:  120nMAssay Description:The PI3K enzymes catalyse the phosphorylation of phosphatidylinositol 4,5-biphosphate (PIP2) to phosphatidylinositol 3,4,5-triphosphate (PIP3) in the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM200639(US9227977, Compound A)
Affinity DataIC50:  193nMAssay Description:The PI3K enzymes catalyse the phosphorylation of phosphatidylinositol 4,5-biphosphate (PIP2) to phosphatidylinositol 3,4,5-triphosphate (PIP3) in the...More data for this Ligand-Target Pair
In DepthDetails US Patent
LigandPNGBDBM200637(US9227977, Compound (Ia))
Affinity DataIC50:  577nMAssay Description:As a means of assessing the activation of PI3K γ in response to stimuli, the phosphorylation status of the protein, Akt, a downstream product of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM200640(US9227977, Example 50)
Affinity DataIC50:  653nMAssay Description:The PI3K enzymes catalyse the phosphorylation of phosphatidylinositol 4,5-biphosphate (PIP2) to phosphatidylinositol 3,4,5-triphosphate (PIP3) in the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM200638(US9227977, Compound (I))
Affinity DataIC50:  4.89E+3nMAssay Description:The PI3K enzymes catalyse the phosphorylation of phosphatidylinositol 4,5-biphosphate (PIP2) to phosphatidylinositol 3,4,5-triphosphate (PIP3) in the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM200638(US9227977, Compound (I))
Affinity DataIC50: >1.39E+4nMAssay Description:The PI3K enzymes catalyse the phosphorylation of phosphatidylinositol 4,5-biphosphate (PIP2) to phosphatidylinositol 3,4,5-triphosphate (PIP3) in the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM200637(US9227977, Compound (Ia))
Affinity DataIC50: >1.42E+4nMAssay Description:As a means of assessing PI3K alpha or beta; activation in response to stimuli, the phosphorylation status of the protein, Akt, a downstream product o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM200637(US9227977, Compound (Ia))
Affinity DataIC50: >1.42E+4nMAssay Description:As a means of assessing PI3K alpha or beta; activation in response to stimuli, the phosphorylation status of the protein, Akt, a downstream product o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent