Compile Data Set for Download or QSAR
maximum 50k data
Found 7 Enz. Inhib. hit(s) with all data for entry = 7585
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate BK) (HCV))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM203919(US9242988, 1)
Affinity DataIC50:  3nMpH: 7.3 T: 2°CAssay Description:To measure inhibition of the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase by the nucleoside triphosphate compounds of the present ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate BK) (HCV))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM203913(US9242988, 22)
Affinity DataIC50:  50nMpH: 7.3 T: 2°CAssay Description:To measure inhibition of the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase by the nucleoside triphosphate compounds of the present ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate BK) (HCV))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM203915(US9242988, 24)
Affinity DataIC50:  87nMpH: 7.3 T: 2°CAssay Description:To measure inhibition of the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase by the nucleoside triphosphate compounds of the present ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate BK) (HCV))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM203914(US9242988, 23)
Affinity DataIC50:  1.20E+3nMpH: 7.3 T: 2°CAssay Description:To measure inhibition of the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase by the nucleoside triphosphate compounds of the present ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate BK) (HCV))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM203918(US9242988, 27)
Affinity DataIC50:  3.80E+3nMpH: 7.3 T: 2°CAssay Description:To measure inhibition of the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase by the nucleoside triphosphate compounds of the present ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate BK) (HCV))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM203916(US9242988, 25)
Affinity DataIC50:  8.70E+4nMpH: 7.3 T: 2°CAssay Description:To measure inhibition of the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase by the nucleoside triphosphate compounds of the present ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus genotype 1b (isolate BK) (HCV))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM203917(US9242988, 26)
Affinity DataIC50: >2.00E+5nMpH: 7.3 T: 2°CAssay Description:To measure inhibition of the enzymatic activity of the HCV NS5B RNA-dependent RNA polymerase by the nucleoside triphosphate compounds of the present ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent