Compile Data Set for Download or QSAR
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Found 5 Enz. Inhib. hit(s) with all data for entry = 7714
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Tennessee Research Foundation

US Patent
LigandPNGBDBM26261((2S)-3-(4-chloro-3-fluorophenoxy)-N-[4-cyano-3-(tr...)
Affinity DataIC50:  1.30E+3nMT: 2°CAssay Description:P450 enzyme inhibition was measured using human cDNA-expressed CYP3A4, 2D6, 2C19, 2C9, and 1A2 recombinant enzymes and fluorogenic substrates (coumar...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2C19(Homo sapiens (Human))
University Of Tennessee Research Foundation

US Patent
LigandPNGBDBM26261((2S)-3-(4-chloro-3-fluorophenoxy)-N-[4-cyano-3-(tr...)
Affinity DataIC50:  2.40E+3nMT: 2°CAssay Description:P450 enzyme inhibition was measured using human cDNA-expressed CYP3A4, 2D6, 2C19, 2C9, and 1A2 recombinant enzymes and fluorogenic substrates (coumar...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2D6(Homo sapiens (Human))
University Of Tennessee Research Foundation

US Patent
LigandPNGBDBM26261((2S)-3-(4-chloro-3-fluorophenoxy)-N-[4-cyano-3-(tr...)
Affinity DataIC50:  1.77E+4nMT: 2°CAssay Description:P450 enzyme inhibition was measured using human cDNA-expressed CYP3A4, 2D6, 2C19, 2C9, and 1A2 recombinant enzymes and fluorogenic substrates (coumar...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2C9(Homo sapiens (Human))
University Of Tennessee Research Foundation

US Patent
LigandPNGBDBM26261((2S)-3-(4-chloro-3-fluorophenoxy)-N-[4-cyano-3-(tr...)
Affinity DataIC50: >2.00E+4nMT: 2°CAssay Description:P450 enzyme inhibition was measured using human cDNA-expressed CYP3A4, 2D6, 2C19, 2C9, and 1A2 recombinant enzymes and fluorogenic substrates (coumar...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 3A4(Homo sapiens (Human))
University Of Tennessee Research Foundation

US Patent
LigandPNGBDBM26261((2S)-3-(4-chloro-3-fluorophenoxy)-N-[4-cyano-3-(tr...)
Affinity DataIC50: >2.00E+4nMT: 2°CAssay Description:P450 enzyme inhibition was measured using human cDNA-expressed CYP3A4, 2D6, 2C19, 2C9, and 1A2 recombinant enzymes and fluorogenic substrates (coumar...More data for this Ligand-Target Pair
In DepthDetails US Patent