Found 8 Enz. Inhib. hit(s) with all data for entry = 7740 TargetDual specificity protein kinase TTK [2-857](Homo sapiens (Human))
Nerviano Medical Sciences
US Patent
Nerviano Medical Sciences
US Patent
Affinity DataIC50: <200nMpH: 7.5Assay Description:The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay. Spec...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK [2-857](Homo sapiens (Human))
Nerviano Medical Sciences
US Patent
Nerviano Medical Sciences
US Patent
Affinity DataIC50: <200nMpH: 7.5Assay Description:The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay. Spec...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK [2-857](Homo sapiens (Human))
Nerviano Medical Sciences
US Patent
Nerviano Medical Sciences
US Patent
Affinity DataIC50: <200nMpH: 7.5Assay Description:The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay. Spec...More data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK [2-857](Homo sapiens (Human))
Nerviano Medical Sciences
US Patent
Nerviano Medical Sciences
US Patent
Affinity DataIC50: <200nMpH: 7.5Assay Description:The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay. Spec...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3 [781-1124](Homo sapiens (Human))
Nerviano Medical Sciences
US Patent
Nerviano Medical Sciences
US Patent
Affinity DataIC50: <5.00E+3nMAssay Description:The assay has been performed using the JAK3 kinase domain (residues 781-1124 of the 1124 amino acid long full-length sequence, accession number P5233...More data for this Ligand-Target Pair
Affinity DataIC50: <5.00E+3nMAssay Description:The assay has been performed using the commercial available JAK2 kinase domain (Invitrogen, Eugene, Oreg.). The JAK2 kinase domain showed a linear ki...More data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMpH: 7.5Assay Description:Kinase Buffer (KB) The buffer for PIM2 assay was composed of HEPES 50 mM, at pH 7.5, with 1 mM MgCl2, 1 mM DTT, 3 uM Na3VO4, and 0.2 mg/mL BSA.Full-l...More data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+4nMpH: 3.0 T: 2°CAssay Description:Dowex Resin Preparation 500 g of wet resin (SIGMA, custom prepared resin DOWEX 1x8 200-400 mesh, 2.5 Kg) are weighed out and diluted to 2 L in 150 mM...More data for this Ligand-Target Pair
