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Found 74 Enz. Inhib. hit(s) with all data for entry = 777
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290224(US9573958, Compound 59)
Affinity DataIC50:  0.600nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290222(US9573958, Compound 20)
Affinity DataIC50:  0.600nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290254(US9573958, Compound 63)
Affinity DataIC50:  1.30nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290231(US9573958, Compound 22)
Affinity DataIC50:  1.80nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290167(US9573958, Compound 113)
Affinity DataIC50:  2.30nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290232(US9573958, Compound 61)
Affinity DataIC50:  2.40nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290242(US9573958, Compound 134)
Affinity DataIC50:  2.60nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290226(US9573958, Compound 21)
Affinity DataIC50:  3nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290235(US9573958, Compound 62)
Affinity DataIC50:  3.5nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290229(US9573958, Compound 60)
Affinity DataIC50:  5nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290185(US9573958, Compound 49)
Affinity DataIC50:  5nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290257(US9573958, Compound 64)
Affinity DataIC50:  5.40nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290164(US9573958, Compound 40)
Affinity DataIC50:  5.60nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290248(US9573958, Compound 136)
Affinity DataIC50:  6nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290149(US9573958, Compound 33)
Affinity DataIC50:  7nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290217(US9573958, Compound 58)
Affinity DataIC50:  7nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290258(US9573958, Compound 85)
Affinity DataIC50:  7.5nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290142(US9573958, Compound 102)
Affinity DataIC50:  7.60nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290181(US9573958, Compound 117)
Affinity DataIC50:  9.30nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290216(US9573958, Compound 19)
Affinity DataIC50:  10nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290171(US9573958, Compound 42)
Affinity DataIC50:  10nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290173(US9573958, Compound 116)
Affinity DataIC50:  10.3nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290186(US9573958, Compound 118)
Affinity DataIC50:  11.8nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290243(US9573958, Compound 26)
Affinity DataIC50:  12nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290193(US9573958, Compound 51)
Affinity DataIC50:  13nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290233(US9573958, Compound 128)
Affinity DataIC50:  13.7nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290161(US9573958, Compound 115)
Affinity DataIC50:  14.5nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290230(US9573958, Compound 127)
Affinity DataIC50:  18nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290237(US9573958, Compound 24)
Affinity DataIC50:  19nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290245(US9573958, Compound 135)
Affinity DataIC50:  19nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290179(US9573958, Compound 44)
Affinity DataIC50:  19.9nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290158(US9573958, Compound 37)
Affinity DataIC50:  20nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290234(US9573958, Compound 23)
Affinity DataIC50:  23nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290256(US9573958, Compound 87)
Affinity DataIC50:  24.8nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290150(US9573958, Compound 108)
Affinity DataIC50:  26nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290203(US9573958, Compound 18)
Affinity DataIC50:  28nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290239(US9573958, Compound 132)
Affinity DataIC50:  28nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290194(US9573958, Compound 121)
Affinity DataIC50:  35nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290189(US9573958, Compound 50)
Affinity DataIC50:  37nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290155(US9573958, Compound 36)
Affinity DataIC50:  40nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290255(US9573958, Compound 86)
Affinity DataIC50:  44nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290253(US9573958, Compound 89)
Affinity DataIC50:  49nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290198(US9573958, Compound 122)
Affinity DataIC50:  52nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290251(US9573958, Compound 138)
Affinity DataIC50:  68nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290197(US9573958, Compound 53)
Affinity DataIC50:  120nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290183(US9573958, Compound 12)
Affinity DataIC50:  120nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290238(US9573958, Compound 68)
Affinity DataIC50:  127nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290195(US9573958, Compound 17)
Affinity DataIC50:  130nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290240(US9573958, Compound 25)
Affinity DataIC50:  137nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM290134(US9573958, Compound 32)
Affinity DataIC50:  142nMpH: 7.5Assay Description:The ability of the compounds of the present disclosure to inhibit ITK was measured using the Caliper assay format, which is an electrophoretic separa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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