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Found 18 Enz. Inhib. hit(s) with all data for entry = 251
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Hudson Biopharma

US Patent
LigandPNGBDBM254012(US9701685, 19 | racemic 4-[(2'R,3R,3'S,5'S)-6-chlo...)
Affinity DataIC50:  3.60nMpH: 7.4 T: 2°CAssay Description:Test compounds (12.34 uM stock in DMSO) were diluted three fold in series in DMSO and 2 ul per well were added into 384-well polypropylene plates (Ma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Hudson Biopharma

US Patent
LigandPNGBDBM254013(US9701685, 20 | US9701685, 22 | racemic (4-carbamo...)
Affinity DataIC50:  3.60nMpH: 7.4 T: 2°CAssay Description:Test compounds (12.34 uM stock in DMSO) were diluted three fold in series in DMSO and 2 ul per well were added into 384-well polypropylene plates (Ma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Hudson Biopharma

US Patent
LigandPNGBDBM254014(US9701685, 21 | chiral 4-[(2'R,3R,3'S,5'S)-6-chlor...)
Affinity DataIC50:  3.60nMpH: 7.4 T: 2°CAssay Description:Test compounds (12.34 uM stock in DMSO) were diluted three fold in series in DMSO and 2 ul per well were added into 384-well polypropylene plates (Ma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Hudson Biopharma

US Patent
LigandPNGBDBM254013(US9701685, 20 | US9701685, 22 | racemic (4-carbamo...)
Affinity DataIC50:  3.60nMpH: 7.4 T: 2°CAssay Description:Test compounds (12.34 uM stock in DMSO) were diluted three fold in series in DMSO and 2 ul per well were added into 384-well polypropylene plates (Ma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Hudson Biopharma

US Patent
LigandPNGBDBM254010(US9701685, 12 | US9701685, 66 | racemic (2''R,3R,3...)
Affinity DataIC50:  3.60nMpH: 7.4 T: 2°CAssay Description:Test compounds (12.34 uM stock in DMSO) were diluted three fold in series in DMSO and 2 ul per well were added into 384-well polypropylene plates (Ma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Hudson Biopharma

US Patent
LigandPNGBDBM254008(US9701685, 10 | US9701685, 65 | racemic 4-[[(2''R,...)
Affinity DataIC50:  3.60nMpH: 7.4 T: 2°CAssay Description:Test compounds (12.34 uM stock in DMSO) were diluted three fold in series in DMSO and 2 ul per well were added into 384-well polypropylene plates (Ma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Hudson Biopharma

US Patent
LigandPNGBDBM254011(US9701685, 13 | US9701685, 28 | racemic (2''R,3R,3...)
Affinity DataIC50:  3.60nMpH: 7.4 T: 2°CAssay Description:Test compounds (12.34 uM stock in DMSO) were diluted three fold in series in DMSO and 2 ul per well were added into 384-well polypropylene plates (Ma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Hudson Biopharma

US Patent
LigandPNGBDBM254009(US9701685, 11 | US9701685, 27 | racemic 4-[[(2''R,...)
Affinity DataIC50:  3.60nMpH: 7.4 T: 2°CAssay Description:Test compounds (12.34 uM stock in DMSO) were diluted three fold in series in DMSO and 2 ul per well were added into 384-well polypropylene plates (Ma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Hudson Biopharma

US Patent
LigandPNGBDBM254024(US9701685, 76 | chiral 4-[[(2'R,3R,3'S,5'S)-6-chlo...)
Affinity DataIC50:  7.20nMpH: 7.4 T: 2°CAssay Description:Test compounds (12.34 uM stock in DMSO) were diluted three fold in series in DMSO and 2 ul per well were added into 384-well polypropylene plates (Ma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Hudson Biopharma

US Patent
LigandPNGBDBM254023(US9701685, 75 | racemic 6-chloro-4'-(3-chloro-2-fl...)
Affinity DataIC50:  7.20nMpH: 7.4 T: 2°CAssay Description:Test compounds (12.34 uM stock in DMSO) were diluted three fold in series in DMSO and 2 ul per well were added into 384-well polypropylene plates (Ma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Hudson Biopharma

US Patent
LigandPNGBDBM254022(US9701685, 74 | racemic 4-{[6-chloro-4'-(3-chloro-...)
Affinity DataIC50:  7.20nMpH: 7.4 T: 2°CAssay Description:Test compounds (12.34 uM stock in DMSO) were diluted three fold in series in DMSO and 2 ul per well were added into 384-well polypropylene plates (Ma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Hudson Biopharma

US Patent
LigandPNGBDBM254021(US9701685, 73 | racemic 4-{[6-chloro-4'-(3-chloro-...)
Affinity DataIC50:  7.20nMpH: 7.4 T: 2°CAssay Description:Test compounds (12.34 uM stock in DMSO) were diluted three fold in series in DMSO and 2 ul per well were added into 384-well polypropylene plates (Ma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Hudson Biopharma

US Patent
LigandPNGBDBM254016(US9701685, 26 | chiral ethyl-4-[[(2'R,3'R,3'S,5'S)...)
Affinity DataIC50:  7.20nMpH: 7.4 T: 2°CAssay Description:Test compounds (12.34 uM stock in DMSO) were diluted three fold in series in DMSO and 2 ul per well were added into 384-well polypropylene plates (Ma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Hudson Biopharma

US Patent
LigandPNGBDBM254011(US9701685, 13 | US9701685, 28 | racemic (2''R,3R,3...)
Affinity DataIC50:  7.20nMpH: 7.4 T: 2°CAssay Description:Test compounds (12.34 uM stock in DMSO) were diluted three fold in series in DMSO and 2 ul per well were added into 384-well polypropylene plates (Ma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Hudson Biopharma

US Patent
LigandPNGBDBM254010(US9701685, 12 | US9701685, 66 | racemic (2''R,3R,3...)
Affinity DataIC50:  7.20nMpH: 7.4 T: 2°CAssay Description:Test compounds (12.34 uM stock in DMSO) were diluted three fold in series in DMSO and 2 ul per well were added into 384-well polypropylene plates (Ma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Hudson Biopharma

US Patent
LigandPNGBDBM254025(US9701685, 77 | chiral (2'R,3R,3'S,5'S)-N-(4-carba...)
Affinity DataIC50:  7.20nMpH: 7.4 T: 2°CAssay Description:Test compounds (12.34 uM stock in DMSO) were diluted three fold in series in DMSO and 2 ul per well were added into 384-well polypropylene plates (Ma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Hudson Biopharma

US Patent
LigandPNGBDBM254008(US9701685, 10 | US9701685, 65 | racemic 4-[[(2''R,...)
Affinity DataIC50:  7.20nMpH: 7.4 T: 2°CAssay Description:Test compounds (12.34 uM stock in DMSO) were diluted three fold in series in DMSO and 2 ul per well were added into 384-well polypropylene plates (Ma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Hudson Biopharma

US Patent
LigandPNGBDBM254009(US9701685, 11 | US9701685, 27 | racemic 4-[[(2''R,...)
Affinity DataIC50:  7.20nMpH: 7.4 T: 2°CAssay Description:Test compounds (12.34 uM stock in DMSO) were diluted three fold in series in DMSO and 2 ul per well were added into 384-well polypropylene plates (Ma...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent