Compile Data Set for Download or QSAR
maximum 50k data
Found 11 Enz. Inhib. hit(s) with all data for entry = 1784
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Crystalgenomics

US Patent
LigandPNGBDBM340036(1-(3-chloro-2,6-difluorophenyl)-3-(3-fluoro- 4-(7-...)
Affinity DataIC50:  0.0500nMAssay Description:In order to evaluate the activity of the compounds of the present invention as a BTK inhibitor, commercially available BTK (Promega) was used for thi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Crystalgenomics

US Patent
LigandPNGBDBM340037(1-(2-chloro-3,6-difluorophenyl)-3-(3-fluoro- 4-(7-...)
Affinity DataIC50:  0.0700nMAssay Description:In order to evaluate the activity of the compounds of the present invention as a BTK inhibitor, commercially available BTK (Promega) was used for thi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Crystalgenomics

US Patent
LigandPNGBDBM340031(1-{3-fluoro-4-[7-(5-methyl-1H-imidazol-2- yl)-1-ox...)
Affinity DataIC50:  0.100nMAssay Description:In order to evaluate the activity of the compounds of the present invention as a BTK inhibitor, commercially available BTK (Promega) was used for thi...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Crystalgenomics

US Patent
LigandPNGBDBM340033(1-{3-fluoro-4-[7-(5-methyl-1H-imidazol-2- yl)-1-ox...)
Affinity DataIC50:  0.280nMAssay Description:In order to evaluate the activity of the compounds of the present invention as a BTK inhibitor, commercially available BTK (Promega) was used for thi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Crystalgenomics

US Patent
LigandPNGBDBM340032(1-{3-fluoro-4-[7-(5-methyl-1H-imidazol-2- yl)-1-ox...)
Affinity DataIC50:  0.400nMAssay Description:In order to evaluate the activity of the compounds of the present invention as a BTK inhibitor, commercially available BTK (Promega) was used for thi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Crystalgenomics

US Patent
LigandPNGBDBM340039(1-{3-fluoro-4-[7-(5-methyl-1H-imidazol-2- yl)-1-ox...)
Affinity DataIC50:  0.900nMAssay Description:In order to evaluate the activity of the compounds of the present invention as a BTK inhibitor, commercially available BTK (Promega) was used for thi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Crystalgenomics

US Patent
LigandPNGBDBM340030(1-(2-chloro-6-fluoro-phenyl)-3-{3-fluoro-4- [7-(5-...)
Affinity DataIC50:  0.900nMAssay Description:In order to evaluate the activity of the compounds of the present invention as a BTK inhibitor, commercially available BTK (Promega) was used for thi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Crystalgenomics

US Patent
LigandPNGBDBM340029(1-(2,6-difluoro-phenyl)-3-{3-fluoro-4-[7-(5- methy...)
Affinity DataIC50:  1nMAssay Description:In order to evaluate the activity of the compounds of the present invention as a BTK inhibitor, commercially available BTK (Promega) was used for thi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Crystalgenomics

US Patent
LigandPNGBDBM340038(1-(4-chloro-2,6-difluoro-phenyl)-3-{3- fluoro-4-[7...)
Affinity DataIC50:  4nMAssay Description:In order to evaluate the activity of the compounds of the present invention as a BTK inhibitor, commercially available BTK (Promega) was used for thi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Crystalgenomics

US Patent
LigandPNGBDBM340035(1-(4-cyano-3-fluorophenyl)-3-(3-fluoro-4- (7-(5-me...)
Affinity DataIC50:  5nMAssay Description:In order to evaluate the activity of the compounds of the present invention as a BTK inhibitor, commercially available BTK (Promega) was used for thi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Crystalgenomics

US Patent
LigandPNGBDBM340034(1-(3,4-difluoro-phenyl)-3-{3-fluoro-4-[7-(5- methy...)
Affinity DataIC50:  5.60nMAssay Description:In order to evaluate the activity of the compounds of the present invention as a BTK inhibitor, commercially available BTK (Promega) was used for thi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent