Compile Data Set for Download or QSAR
maximum 50k data
Found 12 Enz. Inhib. hit(s) with all data for entry = 516
TargetTyrosine-protein kinase BTK/Lck(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM275489(US9879013, 11(3))
Affinity DataIC50:  1.90E+4nMAssay Description:The Btk enzyme inhibitory activity was measured, based on the protocol provided by the manufacturer, using Btk (Invitrogen Corporation) and the ZR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK/Lck(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM275463(US9879013, 8)
Affinity DataIC50:  8.00E+4nMAssay Description:The Btk enzyme inhibitory activity was measured, based on the protocol provided by the manufacturer, using Btk (Invitrogen Corporation) and the ZR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK/Lck(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM194087(US20230364079, Example Tirabrutinib | US9199997, 9...)
Affinity DataIC50:  1.14E+5nMAssay Description:The Btk enzyme inhibitory activity was measured, based on the protocol provided by the manufacturer, using Btk (Invitrogen Corporation) and the ZR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK/Lyn(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM275489(US9879013, 11(3))
Affinity DataIC50:  1.43E+5nMAssay Description:The Btk enzyme inhibitory activity was measured, based on the protocol provided by the manufacturer, using Btk (Invitrogen Corporation) and the ZR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK/Lck(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM275473(US9879013, 8(14))
Affinity DataIC50:  2.20E+5nMAssay Description:The Btk enzyme inhibitory activity was measured, based on the protocol provided by the manufacturer, using Btk (Invitrogen Corporation) and the ZR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK/Fyn(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM275489(US9879013, 11(3))
Affinity DataIC50:  2.36E+5nMAssay Description:The Btk enzyme inhibitory activity was measured, based on the protocol provided by the manufacturer, using Btk (Invitrogen Corporation) and the ZR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK/Fyn(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM275463(US9879013, 8)
Affinity DataIC50:  4.53E+5nMAssay Description:The Btk enzyme inhibitory activity was measured, based on the protocol provided by the manufacturer, using Btk (Invitrogen Corporation) and the ZR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK/Lyn(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM275463(US9879013, 8)
Affinity DataIC50:  4.59E+5nMAssay Description:The Btk enzyme inhibitory activity was measured, based on the protocol provided by the manufacturer, using Btk (Invitrogen Corporation) and the ZR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK/Lyn(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM194087(US20230364079, Example Tirabrutinib | US9199997, 9...)
Affinity DataIC50:  4.71E+5nMAssay Description:The Btk enzyme inhibitory activity was measured, based on the protocol provided by the manufacturer, using Btk (Invitrogen Corporation) and the ZR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK/Fyn(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM194087(US20230364079, Example Tirabrutinib | US9199997, 9...)
Affinity DataIC50:  7.62E+5nMAssay Description:The Btk enzyme inhibitory activity was measured, based on the protocol provided by the manufacturer, using Btk (Invitrogen Corporation) and the ZR...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK/Lyn(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM275473(US9879013, 8(14))
Affinity DataIC50:  1.77E+6nMAssay Description:The Btk enzyme inhibitory activity was measured, based on the protocol provided by the manufacturer, using Btk (Invitrogen Corporation) and the ZR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK/Fyn(Homo sapiens (Human))
Ono Pharmaceutical

US Patent
LigandPNGBDBM275473(US9879013, 8(14))
Affinity DataIC50:  2.50E+6nMAssay Description:The Btk enzyme inhibitory activity was measured, based on the protocol provided by the manufacturer, using Btk (Invitrogen Corporation) and the ZR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent