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Found 3 Enz. Inhib. hit(s) for PDB: 1EP4
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Pfizer

LigandPNGBDBM27579(AG 1549 | CPV | Capravirine | {5-[(3,5-dichlorophe...)
Affinity DataIC50:  47nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Pfizer

LigandPNGBDBM27579(AG 1549 | CPV | Capravirine | {5-[(3,5-dichlorophe...)
Affinity DataIC50:  61nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein [588-1027,K691N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Pfizer

LigandPNGBDBM27579(AG 1549 | CPV | Capravirine | {5-[(3,5-dichlorophe...)
Affinity DataIC50:  68nMpH: 7.8 T: 2°CAssay Description:The inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme was measured using a primer extension assay. Th...More data for this Ligand-Target Pair