Found 4 Enz. Inhib. hit(s) for PDB: 1LCA 
Affinity DataKi: 10nMAssay Description:Compound was tested for inhibition of Thymidylate Synthase in L. casei,More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 60nM ΔG°: -40.5kJ/molepH: 7.4 T: 2°CAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
Affinity DataKi: 60nM ΔG°: -40.5kJ/molepH: 7.0 T: 2°CAssay Description:The inhibition assay pattern for all of the compounds was determined by steady-state kinetic analysis of the dependence of the TS enzyme activity on ...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of Lactobacillus casei thymidylate synthaseMore data for this Ligand-Target Pair
