Compile Data Set for Download or QSAR
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Found 4 Enz. Inhib. hit(s) for PDB: 1T4J
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50341989(3-(3,5-DIBROMO-4-HYDROXY-BENZOYL)-2-ETHYL-BENZOFUR...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of GST-tagged PTP1B (1 to 321 residues) (unknown origin) using p-NPP as substrate preincubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50341989(3-(3,5-DIBROMO-4-HYDROXY-BENZOYL)-2-ETHYL-BENZOFUR...)
Affinity DataIC50:  6.81E+3nMAssay Description:Inhibition of PTP1B (unknown origin) using nitrophenyl phosphate as substrate after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50341989(3-(3,5-DIBROMO-4-HYDROXY-BENZOYL)-2-ETHYL-BENZOFUR...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of recombinant human PTP1B assessed as inhibition of hydrolysis of pNPP by spectrophotometryMore data for this Ligand-Target Pair
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Northeastern University

Curated by ChEMBL
LigandPNGBDBM50341989(3-(3,5-DIBROMO-4-HYDROXY-BENZOYL)-2-ETHYL-BENZOFUR...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair