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Found 2 Enz. Inhib. hit(s) for PDB: 2BXV
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM1542(2-({2-fluoro-4-[3-(trifluoromethoxy)phenyl]phenyl}...)
Affinity DataIC50:  280nMAssay Description:In vitro inhibitory activity against human dihydroorotate dehydrogenase (DHODH)More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Homo sapiens (Human))
4Sc

Curated by ChEMBL
LigandPNGBDBM1542(2-({2-fluoro-4-[3-(trifluoromethoxy)phenyl]phenyl}...)
Affinity DataIC50:  280nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair