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Compile Data Set for Download or QSAR
maximum 50k data
Found
2
Enz. Inhib. hit(s) for PDB:
2IS0
Target
Beta-secretase 1
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM16036
(2-Amino-2-benzyl-3-hydroxypropyl-3-({[(1R)-1-(4-fl...)
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Affinity Data
IC50: 193nM
Assay Description:
Inhibition of BACE1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
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Target
Beta-secretase 1
(Homo sapiens (Human))
Merck Research Laboratories
Curated by
ChEMBL
Ligand
BDBM16036
(2-Amino-2-benzyl-3-hydroxypropyl-3-({[(1R)-1-(4-fl...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 200nM
pH: 4.5 T: 2°C
Assay Description:
For BACE activity assay using recombinant MBP-APP_NFEV substrate, BACE was incubated with purified MBP-APP_NFEV substrate in reaction buffer containi...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
PDB
Similars
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI