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Found 3 Enz. Inhib. hit(s) for PDB: 2R7B
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM19087(15,16-dimethoxy-6-methyl-8,12-diazatetracyclo[8.8....)
Affinity DataIC50:  60nMpH: 7.4 T: 2°CAssay Description:A homogeneous in vitro assay based on a LANCE format was first used for high-throughput screening. Those compounds that showed the largest different...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM19087(15,16-dimethoxy-6-methyl-8,12-diazatetracyclo[8.8....)
Affinity DataIC50:  60nMAssay Description:Inhibition of PDK1 (unknown origin)More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM19087(15,16-dimethoxy-6-methyl-8,12-diazatetracyclo[8.8....)
Affinity DataIC50:  60nMAssay Description:Inhibition of human GST-tagged-PDK1 expressed in HEK293 cellsMore data for this Ligand-Target Pair