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Compile Data Set for Download or QSAR
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Found
1
Enz. Inhib. hit(s) for PDB:
2V12
Target
Renin
(Homo sapiens (Human))
Novartis Pharmaceuticals
Ligand
BDBM17948
((2R,4S,5S,7S)-5-amino-N-butyl-4-hydroxy-7-({[2-(3-...)
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Affinity Data
IC50: 0.900nM
pH: 7.2 T: 2°C
Assay Description:
In vitro potencies of compounds against purified human recombinant renin were determined by its cleavage of substrate angiotensinogen. The angiotensi...
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