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Found 1 Enz. Inhib. hit(s) for PDB: 2WOT
TargetTGF-beta receptor type-1(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM35939(4-pyridinoxy-2-anilinopyridine-based compound, 1)
Affinity DataIC50:  44nM EC50:  55nMpH: 7.4 T: 2°CAssay Description:A fluorescence polarization assay was used to assess the ALK5 binding capacity and biochemical activity of compounds. ALK5 protein was added to each ...More data for this Ligand-Target Pair