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Found 3 Enz. Inhib. hit(s) for PDB: 3HRF
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Universit£Tsklinikum Frankfurt

LigandPNGBDBM50296949((2Z)-5-(4-chlorophenyl)-3-phenylpent-2-enoic acid ...)
Affinity DataIC50:  9.70E+4nMpH: 7.4 T: 2°CAssay Description:The AlphaScreen Assay (Perkin Elmer) was performed according to the manufacturer's protocol in 384-well microtiter plates. Incubations were performe...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Universit£Tsklinikum Frankfurt

LigandPNGBDBM50296949((2Z)-5-(4-chlorophenyl)-3-phenylpent-2-enoic acid ...)
Affinity DataKd:  1.03E+4nMAssay Description:Binding affinity to human PDPK1 Y288G/Q292A mutant expressed in insect cell system assessed as substrate phosphorylation by isothermal titration calo...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Universit£Tsklinikum Frankfurt

LigandPNGBDBM50296949((2Z)-5-(4-chlorophenyl)-3-phenylpent-2-enoic acid ...)
Affinity DataKd:  1.03E+4nMAssay Description:Binding affinity to PDK1 (50 to 359) by isothermal titration calorimetryMore data for this Ligand-Target Pair