Compile Data Set for Download or QSAR
maximum 50k data
Found 2 Enz. Inhib. hit(s) for PDB: 3R4M
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343360(4-Chloro-6-(2-methoxyphenyl)-pyrimidin-2-ylamine |...)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [3H]-(R)-2-(5-chloro-2,4-dihydroxybenzoyl)-N-ethylisoindoline-1-carboxamide from human his(6)-tagged HSP90alpha after 30 mins by scin...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Homo sapiens (Human))
Astex Therapeutics

Curated by ChEMBL
LigandPNGBDBM50343360(4-Chloro-6-(2-methoxyphenyl)-pyrimidin-2-ylamine |...)
Affinity DataKd:  350nMAssay Description:Binding affinity to human N-terminal ATPase domain of Hsp90 by isothermal titration calorimetryMore data for this Ligand-Target Pair