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Found 7 Enz. Inhib. hit(s) for PDB: 3S7S
TargetAromatase(Homo sapiens (Human))
The M. S. University Of Baroda

Curated by ChEMBL
LigandPNGBDBM50398447(Aromasin | EXEMESTANE)
Affinity DataKi:  10nMAssay Description:Competitive inhibition of human aromatase extracted from placental microsomesMore data for this Ligand-Target Pair
TargetAromatase(Homo sapiens (Human))
The M. S. University Of Baroda

Curated by ChEMBL
LigandPNGBDBM50398447(Aromasin | EXEMESTANE)
Affinity DataKi:  26nMAssay Description:Irreversible inhibition of human aromatase extracted from placental microsomesMore data for this Ligand-Target Pair
TargetAromatase(Homo sapiens (Human))
The M. S. University Of Baroda

Curated by ChEMBL
LigandPNGBDBM50398447(Aromasin | EXEMESTANE)
Affinity DataIC50:  43nMAssay Description:Inhibition of purified HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
TargetAromatase(Homo sapiens (Human))
The M. S. University Of Baroda

Curated by ChEMBL
LigandPNGBDBM50398447(Aromasin | EXEMESTANE)
Affinity DataIC50:  50nMAssay Description:Inhibition of human placental microsome aromatase using [1beta-3H] androstenedione as substrate after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
TargetAromatase(Homo sapiens (Human))
The M. S. University Of Baroda

Curated by ChEMBL
LigandPNGBDBM50398447(Aromasin | EXEMESTANE)
Affinity DataIC50:  50.1nMAssay Description:Inhibition of human placental aromatase using [3H]-1beta-androstenedione as substrate after 16 hrs by [3H]-water methodMore data for this Ligand-Target Pair
TargetAromatase(Homo sapiens (Human))
The M. S. University Of Baroda

Curated by ChEMBL
LigandPNGBDBM50398447(Aromasin | EXEMESTANE)
Affinity DataIC50:  230nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
TargetAromatase(Homo sapiens (Human))
The M. S. University Of Baroda

Curated by ChEMBL
LigandPNGBDBM50398447(Aromasin | EXEMESTANE)
Affinity DataIC50:  900nMAssay Description:Inhibition of human placental microsome aromatase expressed in human MCF7 cells using [1beta-3H] androstenedione as substrate after 1 hr by liquid sc...More data for this Ligand-Target Pair