Compile Data Set for Download or QSAR
maximum 50k data
Found 2 Enz. Inhib. hit(s) for PDB: 4B70
TargetBeta-secretase 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50491243(CHEMBL2380444)
Affinity DataIC50:  790nMAssay Description:Inhibition of BACE1-mediated soluble APPbeta release in human SH-SY5Y cells after 16 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetBeta-secretase 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50491243(CHEMBL2380444)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of human BACE1 (1-460) using CEVNLDAEFK as substrate preincubated for 10 mins prior to substrate addition measured after 15 mins by TR-FRE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB