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Found 2 Enz. Inhib. hit(s) for PDB: 4IWZ
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Istanbul University

Curated by ChEMBL
LigandPNGBDBM35732(sulfonamide deriv., 6)
Affinity DataKi:  51nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Istanbul University

Curated by ChEMBL
LigandPNGBDBM35732(sulfonamide deriv., 6)
Affinity DataKi:  51nM ΔG°:  -41.6kJ/molepH: 7.4 T: 2°CAssay Description:An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...More data for this Ligand-Target Pair