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Found 3 Enz. Inhib. hit(s) for PDB: 4K9Y
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50440370(CHEMBL2425144)
Affinity DataIC50:  266nMAssay Description:Inhibition of FAK (unknown origin) using biotinylated-His-TEVhsFAK(31-686)(K454R) as substrate after 2 hrs by scintillation counting analysisMore data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50440370(CHEMBL2425144)
Affinity DataIC50:  750nMAssay Description:Inhibition of FAK in human HT-29 cells assessed as Tyr397 phosphorylation after 45 minsMore data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Merck

Curated by ChEMBL
LigandPNGBDBM50440370(CHEMBL2425144)
Affinity DataKd:  111nMAssay Description:Binding affinity to FAK kinase (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair