Compile Data Set for Download or QSAR
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Found 4 Enz. Inhib. hit(s) for PDB: 4O0V
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50448771(CHEMBL3128042)
Affinity DataKi:  3.30nMAssay Description:Binding affinity to N-terminal GST-tagged recombinant human PAK4 kinase domain expressed in Escherichia coli using KKRNRRLSVA as substrate preincubat...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50448771(CHEMBL3128042)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of human recombinant PAK4 kinase domain assessed as phosphorylation of FRET peptide substrate at Ser/Thr20 by Zylite assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50448771(CHEMBL3128042)
Affinity DataIC50:  7.5nMAssay Description:Inhibition of PAK4 (unknown origin)More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 5(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50448771(CHEMBL3128042)
Affinity DataIC50:  126nMAssay Description:Inhibition of PAK5 (unknown origin)More data for this Ligand-Target Pair