Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) for PDB: 4PX2
TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50500194(CHEMBL3746716)
Affinity DataIC50:  870nMAssay Description:Binding affinity to human biotinylated AviTag GKRP assessed as inhibition of protein interaction with fluorescein tagged human glucokinase by AlphaSc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50500197(CHEMBL3746823)
Affinity DataIC50:  1.20E+3nMAssay Description:Binding affinity to human biotinylated AviTag GKRP assessed as inhibition of protein interaction with fluorescein tagged human glucokinase by AlphaSc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50500197(CHEMBL3746823)
Affinity DataKd:  1.10E+3nMAssay Description:Binding affinity to human GKRP by surface plasmon resonance analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetGlucokinase regulatory protein(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50500197(CHEMBL3746823)
Affinity DataEC50:  260nMAssay Description:Binding affinity to human GKRP assessed as inhibition of protein interaction with human glucokinase by measuring ATP depletion after 60 mins by lucif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB