Compile Data Set for Download or QSAR
maximum 50k data
Found 3 Enz. Inhib. hit(s) for PDB: 4QOC
LigandPNGBDBM50448945(CHEMBL3125521 | US9296736, 381 | US9593129, Exampl...)
Affinity DataIC50:  0.100nMpH: 7.4 T: 2°CAssay Description:The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2 [1-188](Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM50448945(CHEMBL3125521 | US9296736, 381 | US9593129, Exampl...)
Affinity DataIC50:  0.100nMAssay Description:The standard assay conditions for the in vitro HTRF assay consisted of a 50 ul total reaction volume in black 384-well Costar polypropylene plates in...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50448945(CHEMBL3125521 | US9296736, 381 | US9593129, Exampl...)
Affinity DataIC50:  0.100nMAssay Description:Binding affinity to human GST-thrombin-tagged MDM2 assessed as inhibition of interaction with human p53 after 1 hr by HTRF assayMore data for this Ligand-Target Pair