Found 8 Enz. Inhib. hit(s) for PDB: 4WUY 
Affinity DataIC50: <15nMAssay Description:Inhibition of SMYD2 (unknown origin) using p53 (361 to 380) as substrate assessed as incorporation of tritium labeled methyl group from [3H]-SAM to p...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: <15nMAssay Description:Inhibition of SMYD2 (unknown origin) expressed in Escherichia coli BL21 (DE3) using Biotinaminohexanoyl-GSRAHSSHLKSKKGQSTSRH as substrate after 75 mi...More data for this Ligand-Target Pair
Affinity DataIC50: <15nMAssay Description:Inhibition of SMYD2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Inhibition of SMYD2 (unknown origin) by HMT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 388nMAssay Description:Inhibition of SMYD2 (unknown origin) using H4 as substrate after 2hrs in presence 3H-SAM of by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of SMYD2 (unknown origin) expressed in human U2OS cells assessed as reduction in p53 methylation by Western blot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of SMYD2 in human KYSE-150 cells assessed as reduction of monomethylation of p53 K370 by sandwich ELISA methodMore data for this Ligand-Target Pair
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of SMYD2 (unknown origin) using H4 as substrate after 2hrs in presence 3H-SAM of by scintillation proximity assayMore data for this Ligand-Target Pair
