Compile Data Set for Download or QSAR
maximum 50k data
Found 5 Enz. Inhib. hit(s) for PDB: 5G0P
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM190668(US10759791, Compound 14k | nNOS inhibitor, 6)
Affinity DataKi:  25nMAssay Description:Inhibition of rat recombinant nNOS expressed in Escherichia coli using L-arginine as substrate assessed as reduction in NO production measured for 6 ...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM190668(US10759791, Compound 14k | nNOS inhibitor, 6)
Affinity DataKi:  25.2nM ΔG°:  -45.1kJ/molepH: 7.4 T: 2°CAssay Description:The assay was performed at 37 °C in HEPES buffer (100 mM, with 10% glycerol, pH 7.4) in the presence of 10 uM L-arginine. Also included were 100 ...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM190668(US10759791, Compound 14k | nNOS inhibitor, 6)
Affinity DataKi:  37nMAssay Description:Inhibition of human recombinant nNOS expressed in Escherichia coli using L-arginine as substrate assessed as reduction in NO production measured for ...More data for this Ligand-Target Pair
TargetNitric oxide synthase, brain [D597N](Rattus norvegicus (rat))
University Of California Irvine

LigandPNGBDBM190668(US10759791, Compound 14k | nNOS inhibitor, 6)
Affinity DataKi:  97.5nM ΔG°:  -41.6kJ/molepH: 7.4 T: 2°CAssay Description:The assay was performed at 37 °C in HEPES buffer (100 mM, with 10% glycerol, pH 7.4) in the presence of 10 uM L-arginine. Also included were 100 ...More data for this Ligand-Target Pair
TargetIsoform PNNOS of Nitric oxide synthase, brain (PNNOS) -973,I269V,M336V,D597N](Rattus norvegicus (rats))
University Of California Irvine

LigandPNGBDBM190668(US10759791, Compound 14k | nNOS inhibitor, 6)
Affinity DataKi:  108nM ΔG°:  -41.4kJ/molepH: 7.4 T: 2°CAssay Description:The assay was performed at 37 °C in HEPES buffer (100 mM, with 10% glycerol, pH 7.4) in the presence of 10 uM L-arginine. Also included were 100 ...More data for this Ligand-Target Pair