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Found 3 Enz. Inhib. hit(s) for PDB: 5TE8
TargetCytochrome P450 3A4(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM21363(12-chloro-9-(2-fluorophenyl)-3-methyl-2,4,8-triaza...)
Affinity DataKi:  2.47E+3nMAssay Description:Inhibition of human recombinant CYP3A4 in liver microsomes by mechanism based inhibition assayMore data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM21363(12-chloro-9-(2-fluorophenyl)-3-methyl-2,4,8-triaza...)
Affinity DataIC50:  8.10E+3nMAssay Description:Inhibition of human cytochrome P450 3A4More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Sanofi

Curated by ChEMBL
LigandPNGBDBM21363(12-chloro-9-(2-fluorophenyl)-3-methyl-2,4,8-triaza...)
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomeMore data for this Ligand-Target Pair