Affinity DataKi: 4.60nMAssay Description:Competitive inhibition of Aurora C ATP binding siteMore data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Inhibition of aurora CMore data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Inhibition of aurora C (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Inhibition of Aurora C kinaseMore data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Inhibition of Aurora CMore data for this Ligand-Target Pair
Affinity DataKi: 4.60nM ΔG°: -47.1kJ/molepH: 7.5 T: 2°CAssay Description:The kinase activity was determined by incubation of enzyme and its substrate, and test compound, in the presence ATP/[gamma-32P] ATP. After incubatio...More data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:Inhibition of aurora C kinaseChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataKi: 4.60nMAssay Description:In vitro inhibition constant for Aurora-CMore data for this Ligand-Target Pair
Affinity DataIC50: 18.3nMAssay Description:In vitro kinase assay of Aurora A, B, and C using Z-LYTE technology (Invitrogen) and ATP at Km apparent for each kinase.More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:In vitro kinase assay using human aurora kinase in a standard radiometric assay.More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of Aurora C in the presence of 100uM ATPMore data for this Ligand-Target Pair
Affinity DataKd: 6.30nMAssay Description:Binding constant for full-length AURKCMore data for this Ligand-Target Pair
Affinity DataKd: 6.30nMAssay Description:Binding constant for AURKC kinase domainMore data for this Ligand-Target Pair
Affinity DataKd: 6nMAssay Description:Binding affinity to Aurora C kinase catalytic domain by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKd: 6.30nMpH: 7.4 T: 2°CAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair