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Found 4 Enz. Inhib. hit(s) with all data for entry = 50008496
TargetDNA topoisomerase 1(Homo sapiens (Human))
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50073857(3,9-dihydroxy-12-(3,4,5-trihydroxy-6-hydroxymethyl...)
Affinity DataIC50:  1.50E+3nMAssay Description:Concentration of the compound required to inhibit human DNA topoisomerase I (Topo I)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50073854(2,10-dihydroxy-12-(3,4,5-trihydroxy-6-hydroxymethy...)
Affinity DataIC50:  2.30E+3nMAssay Description:Concentration of the compound required to inhibit human DNA topoisomerase I (Topo I)More data for this Ligand-Target Pair
TargetDNA topoisomerase 1(Homo sapiens (Human))
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50073855(1,11-dihydroxy-12-(3,4,5-trihydroxy-6-hydroxymethy...)
Affinity DataIC50:  1.30E+4nMAssay Description:Concentration of the compound required to inhibit human DNA topoisomerase I (Topo I)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Medichem Research

Curated by ChEMBL
LigandPNGBDBM50073856(4,8-dihydroxy-12-(3,4,5-trihydroxy-6-hydroxymethyl...)
Affinity DataIC50:  3.60E+4nMAssay Description:Concentration of the compound required to inhibit human DNA topoisomerase I (Topo I)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed