Compile Data Set for Download or QSAR
maximum 50k data
Found 16 Enz. Inhib. hit(s) with all data for entry = 50003557
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50366779(METHYLLYCACONITINE)
Affinity DataKi:  0.600nMAssay Description:Binding affinity against alpha7 nAChR (nicotinic acetylcholine receptor) using [3H]-MLA as a radioligand relative to alpha4-beta2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50366779(METHYLLYCACONITINE)
Affinity DataKi:  0.800nMAssay Description:Binding affinity against alpha-7 nAChR (nicotinic acetylcholine receptor) using [125I]-alpha-BGT as a radioligand relative to alpha4-beta2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50472784(METHYLLYCACONITINE[3H] MLA | [3H]-MLA)
Affinity DataKi:  0.980nMAssay Description:Inhibition of [3H]MLA binding in presence of methylcaconitine.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50472783(CHEMBL2112068)
Affinity DataKi:  1.30nMAssay Description:Binding affinity against alpha-7 nAChR (nicotinic acetylcholine receptor) using [125I]-alpha-BGT as a radioligand relative to alpha4-beta2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50472783(CHEMBL2112068)
Affinity DataKi:  1.60nMAssay Description:Binding affinity against alpha7 nAChR (nicotinic acetylcholine receptor) using [3H]-MLA as a radioligand relative to alpha4-beta2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50472784(METHYLLYCACONITINE[3H] MLA | [3H]-MLA)
Affinity DataKi:  1.80nMAssay Description:Inhibition of [3H]MLA binding in presence of alpha-bungarotoxinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001942(CHEMBL2113668 | Iodo-MLA)
Affinity DataKi:  1.90nMAssay Description:Inhibition of [125I]iodo-MLA binding in presence of alpha-bungarotoxinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001942(CHEMBL2113668 | Iodo-MLA)
Affinity DataKi:  3.20nMAssay Description:Inhibition of [125I]iodo-MLA binding in presence of methylcaconitine.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001942(CHEMBL2113668 | Iodo-MLA)
Affinity DataKi:  13nMAssay Description:Inhibition of [125I]iodo-MLA binding in presence of 3-cinnamylidene-anabasineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001942(CHEMBL2113668 | Iodo-MLA)
Affinity DataKi:  667nMAssay Description:Inhibition of [125I]iodo-MLA binding in presence of (-)-nicotineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50366779(METHYLLYCACONITINE)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity against alpha-7 nAChR (nicotinic acetylcholine receptor) using [3H]epibatidine as a radioligand relative to alpha4-beta2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50472783(CHEMBL2112068)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity against alpha-7 nAChR (nicotinic acetylcholine receptor) using [3H]epibatidine as a radioligand relative to alpha4-beta2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50472784(METHYLLYCACONITINE[3H] MLA | [3H]-MLA)
Affinity DataKi:  6.07E+3nMAssay Description:Inhibition of [3H]MLA binding in presence of (-)-nicotineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001942(CHEMBL2113668 | Iodo-MLA)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [125I]iodo-MLA binding in presence of dihydro-beta-erythroidineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50001942(CHEMBL2113668 | Iodo-MLA)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of [125I]iodo-MLA binding in presence of mecamylamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rattus norvegicus (Rat))
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50472784(METHYLLYCACONITINE[3H] MLA | [3H]-MLA)
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of [3H]MLA binding in presence of mecamylamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed