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PubMed code 10762038

Compile data set for download or QSAR
Found 3 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Retinoid receptor


(Homo sapiens (Human))
BDBM31883
PNG
(9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...)
Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O
Show InChI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+
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Article
PubMed
n/an/a 0.5n/an/an/an/an/an/a



Eisai Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of [3H]-ATRA-Hl60 binding to Retinoic acid receptor gamma


Bioorg Med Chem Lett 10: 619-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00066-4
BindingDB Entry DOI: 10.7270/Q23T9GFV
More data for this
Ligand-Target Pair
Retinoid X receptor gamma/retinoic acid receptor alpha


(Homo sapiens (Human))
BDBM31883
PNG
(9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...)
Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O
Show InChI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+
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Article
PubMed
n/an/a 0.780n/an/an/an/an/an/a



Eisai Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of [3H]-ATRA-Hl60 binding to Retinoic acid receptor alpha


Bioorg Med Chem Lett 10: 619-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00066-4
BindingDB Entry DOI: 10.7270/Q23T9GFV
More data for this
Ligand-Target Pair
Retinoid receptor


(Homo sapiens (Human))
BDBM31883
PNG
(9-cis-retinoic acid (9cRA) | ALL-TRANS-RETINOIC AC...)
Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O
Show InChI InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14+
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CHEBI
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KEGG
MMDB
PC cid
PC sid
UniChem

Patents


Similars

MMDB
Article
PubMed
n/an/a 0.900n/an/an/an/an/an/a



Eisai Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of [3H]-ATRA-Hl60 binding to Retinoic acid receptor beta


Bioorg Med Chem Lett 10: 619-22 (2000)


Article DOI: 10.1016/s0960-894x(00)00066-4
BindingDB Entry DOI: 10.7270/Q23T9GFV
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%