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Found 11 Enz. Inhib. hit(s) with all data for entry = 50010660
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50097342(3-Chloro-4-[4-(3',6'-dihydro-2'H-[2,4']bipyridinyl...)
Affinity DataIC50:  0.470nMAssay Description:Binding affinity of the compound to 5-hydroxytryptamine 1A receptor of rat hippocampus with [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50097341(3-Chloro-4-[4-(4-pyridin-2-yl-piperazin-1-yl)-buty...)
Affinity DataIC50:  0.770nMAssay Description:Binding affinity of the compound to 5-hydroxytryptamine 1A receptor of rat hippocampus with [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50097343(3-Chloro-4-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-bu...)
Affinity DataIC50:  1.60nMAssay Description:Binding affinity of the compound to 5-hydroxytryptamine 1A receptor of rat hippocampus with [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50097345(3-Methyl-4-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-bu...)
Affinity DataIC50:  10nMAssay Description:Binding affinity of the compound to 5-hydroxytryptamine 1A receptor of rat hippocampus with [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50001859((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...)
Affinity DataIC50:  11nMAssay Description:Binding affinity of the compound to 5-hydroxytryptamine 1A receptor of rat hippocampus with [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50097344(4-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-4H-b...)
Affinity DataIC50:  18nMAssay Description:Binding affinity of the compound to 5-hydroxytryptamine 1A receptor of rat hippocampus with [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50097341(3-Chloro-4-[4-(4-pyridin-2-yl-piperazin-1-yl)-buty...)
Affinity DataIC50:  51nMAssay Description:Binding affinity of the compound to Dopamine receptor D2 in of rat striatum membrane with [3H]- raclopride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50001859((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...)
Affinity DataIC50:  55nMAssay Description:Binding affinity of the compound to Dopamine receptor D2 in of rat striatum membrane with [3H]- raclopride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50097342(3-Chloro-4-[4-(3',6'-dihydro-2'H-[2,4']bipyridinyl...)
Affinity DataIC50:  84nMAssay Description:Binding affinity of the compound to Dopamine receptor D2 in of rat striatum membrane with [3H]- raclopride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50097343(3-Chloro-4-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-bu...)
Affinity DataIC50:  199nMAssay Description:Binding affinity of the compound to Dopamine receptor D2 in of rat striatum membrane with [3H]- raclopride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Suntory Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50097345(3-Methyl-4-[4-(4-pyrimidin-2-yl-piperazin-1-yl)-bu...)
Affinity DataIC50:  1.10E+3nMAssay Description:Binding affinity of the compound to Dopamine receptor D2 in of rat striatum membrane with [3H]- raclopride as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed