Compile Data Set for Download or QSAR
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Found 28 Enz. Inhib. hit(s) with all data for entry = 50037074
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity towards recombinant human Opioid receptor delta 1 transfected in to CHO cells for the displacement of [3H]Cl-DPDPE (delta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50108791(18-cyclopropylmethyl-5-phenyl-10-oxa-7,18-diazahex...)
Affinity DataKi:  2.70nMAssay Description:Binding affinity towards recombinant human Opioid receptor delta 1 transfected in to CHO cells for the displacement of [3H]Cl-DPDPE (delta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Affinity DataKi:  6.30nMAssay Description:Maximum % effect of standard (DAMGO) was reported against Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Affinity DataKi:  10nMAssay Description:Binding affinity towards recombinant human Opioid receptor kappa 1 transfected in to CHO cells for the displacement of [3H]U-69593More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50108788(7-benzyl-18-cyclopropylmethyl-5-phenyl-10-oxa-7,18...)
Affinity DataKi:  14nMAssay Description:Binding affinity towards recombinant humanOpioid receptor delta 1 transfected in to CHO cells for the displacement of [3H]Cl-DPDPE (delta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50108787(7-benzyl-18-cyclopropylmethyl-6-methyl-5-phenyl-10...)
Affinity DataKi:  17nMAssay Description:Binding affinity towards recombinant human Opioid receptor delta 1 transfected in to CHO cells for the displacement of [3H]Cl-DPDPE (delta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50108788(7-benzyl-18-cyclopropylmethyl-5-phenyl-10-oxa-7,18...)
Affinity DataKi:  17nMAssay Description:Maximum % effect of standard (DAMGO) was reported against Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50108792(7-benzyl-5-phenyl-18-propyl-10-oxa-7,18-diazahexac...)
Affinity DataKi:  21nMAssay Description:Binding affinity towards recombinant human Opioid receptor delta 1 transfected in to CHO cells for the displacement of [3H]Cl-DPDPE (delta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50108791(18-cyclopropylmethyl-5-phenyl-10-oxa-7,18-diazahex...)
Affinity DataKi:  21nMAssay Description:Maximum % effect of standard (DAMGO) was reported against Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50108789(7-benzyl-18-cyclopropylmethyl-5-(4-methylphenyl)-1...)
Affinity DataKi:  24nMAssay Description:Binding affinity towards recombinant human Opioid receptor delta 1 transfected in to CHO cells for the displacement of [3H]Cl-DPDPE (delta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50108792(7-benzyl-5-phenyl-18-propyl-10-oxa-7,18-diazahexac...)
Affinity DataKi:  40nMAssay Description:Maximum % effect of standard (DAMGO) was reported against Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50108791(18-cyclopropylmethyl-5-phenyl-10-oxa-7,18-diazahex...)
Affinity DataKi:  45nMAssay Description:Binding affinity towards recombinant human Opioid receptor kappa 1 transfected in to CHO cells for the displacement of [3H]U-69593More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50108790(7-benzyl-18-methyl-5-phenyl-10-oxa-7,18-diazahexac...)
Affinity DataKi:  50nMAssay Description:Maximum % effect of standard (DAMGO) was reported against Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50108787(7-benzyl-18-cyclopropylmethyl-6-methyl-5-phenyl-10...)
Affinity DataKi:  53nMAssay Description:Maximum % effect of standard (DAMGO) was reported against Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50108789(7-benzyl-18-cyclopropylmethyl-5-(4-methylphenyl)-1...)
Affinity DataKi:  78nMAssay Description:Binding affinity towards recombinant human Opioid receptor mu 1 transfected in to CHO cells for the displacement of [3H]DAMGO (mu)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50108789(7-benzyl-18-cyclopropylmethyl-5-(4-methylphenyl)-1...)
Affinity DataKi:  108nMAssay Description:Binding affinity towards recombinant human Opioid receptor kappa 1 transfected in to CHO cells for the displacement of [3H]U-69593More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50108790(7-benzyl-18-methyl-5-phenyl-10-oxa-7,18-diazahexac...)
Affinity DataKi:  116nMAssay Description:Binding affinity towards recombinant human Opioid receptor delta 1 transfected in to CHO cells for the displacement of [3H]Cl-DPDPE (delta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50108788(7-benzyl-18-cyclopropylmethyl-5-phenyl-10-oxa-7,18...)
Affinity DataKi:  120nMAssay Description:Binding affinity towards recombinant human Opioid receptor kappa 1 transfected in to CHO cells for the displacement of [3H]U-69593More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50108787(7-benzyl-18-cyclopropylmethyl-6-methyl-5-phenyl-10...)
Affinity DataKi:  183nMAssay Description:Binding affinity towards recombinant human Opioid receptor kappa 1 transfected in to CHO cells for the displacement of [3H]U-69593More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50108790(7-benzyl-18-methyl-5-phenyl-10-oxa-7,18-diazahexac...)
Affinity DataKi:  187nMAssay Description:Binding affinity towards recombinant human Opioid receptor kappa 1 transfected in to CHO cells for the displacement of [3H]U-69593More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50108792(7-benzyl-5-phenyl-18-propyl-10-oxa-7,18-diazahexac...)
Affinity DataKi:  191nMAssay Description:Binding affinity towards recombinant human Opioid receptor kappa 1 transfected in to CHO cells for the displacement of [3H]U-69593More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50108793(7-benzyl-12-methoxy-18-methyl-5-phenyl-10-oxa-7,18...)
Affinity DataKi:  322nMAssay Description:Binding affinity towards recombinant human Opioid receptor delta 1 transfected in to CHO cells for the displacement of [3H]Cl-DPDPE (delta)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50108793(7-benzyl-12-methoxy-18-methyl-5-phenyl-10-oxa-7,18...)
Affinity DataKi: >1.00E+4nMAssay Description:Maximum % effect of standard (DAMGO) was reported against Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50108793(7-benzyl-12-methoxy-18-methyl-5-phenyl-10-oxa-7,18...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity towards recombinant human Opioid receptor kappa 1 transfected in to CHO cells for the displacement of [3H]U-69593More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50108790(7-benzyl-18-methyl-5-phenyl-10-oxa-7,18-diazahexac...)
Affinity DataEC50:  55nMAssay Description:Partial agonist activity tested in [35S]GTP-gamma-S, Recombinant Human Opioid receptor delta 1 transfected in to CHO cells for the displacement of [3...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50108789(7-benzyl-18-cyclopropylmethyl-5-(4-methylphenyl)-1...)
Affinity DataEC50:  34nMAssay Description:Maximum % effect of standard (DAMGO) was reported against Opioid receptor mu 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50108789(7-benzyl-18-cyclopropylmethyl-5-(4-methylphenyl)-1...)
Affinity DataEC50:  1.36E+3nMAssay Description:The partial agonist activity tested in [35S]-GTP-gamma S Recombinant Human Opioid receptor mu 1 transfected in to CHO cells for the displacement of [...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
University Of Bristol

Curated by ChEMBL
LigandPNGBDBM50108790(7-benzyl-18-methyl-5-phenyl-10-oxa-7,18-diazahexac...)
Affinity DataEC50:  41nMAssay Description:Maximum percentage effect of standard Opioid receptor delta 1 (Cl-DPDPE)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed