Compile Data Set for Download or QSAR
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Found 100 Enz. Inhib. hit(s) with all data for entry = 50041319
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057618(4-[5-(3-Methyl-4-methylsulfanyl-phenyl)-3-trifluor...)
Affinity DataIC50:  3.72nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057606(4-[4-Chloro-5-(4-chloro-phenyl)-3-trifluoromethyl-...)
Affinity DataIC50:  5.25nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057575(4-[5-(4-Dimethylamino-3-fluoro-phenyl)-3-trifluoro...)
Affinity DataIC50:  5.75nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057589(4-[5-(4-Methoxy-phenyl)-3-trifluoromethyl-pyrazol-...)
Affinity DataIC50:  7.94nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057591(4-[5-(4-Methylsulfanyl-phenyl)-3-trifluoromethyl-p...)
Affinity DataIC50:  8.91nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057620(4-[5-(4-Methoxy-3-methyl-phenyl)-3-trifluoromethyl...)
Affinity DataIC50:  9.33nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057572(4-[4-Chloro-5-(4-chloro-phenyl)-3-cyano-pyrazol-1-...)
Affinity DataIC50:  10nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057527(4-(5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  10nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057560(4-[5-(3,4-Dichloro-phenyl)-3-trifluoromethyl-pyraz...)
Affinity DataIC50:  15.1nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057573(4-[5-(4-Methylamino-phenyl)-3-trifluoromethyl-pyra...)
Affinity DataIC50:  15.8nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057592(4-[5-(2,3-Dihydro-benzofuran-5-yl)-3-trifluorometh...)
Affinity DataIC50:  20.9nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057544(4-[5-(3,5-Dichloro-4-methoxy-phenyl)-3-difluoromet...)
Affinity DataIC50:  20.9nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057553(4-[5-(4-Chloro-phenyl)-4-methyl-3-trifluoromethyl-...)
Affinity DataIC50:  21.9nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057605(4-[5-(5-Chloro-thiophen-2-yl)-3-trifluoromethyl-py...)
Affinity DataIC50:  25.7nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057596(4-[5-(3-Chloro-4-methoxy-phenyl)-3-difluoromethyl-...)
Affinity DataIC50:  26.9nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057541(4-[5-(3-Chloro-4-methylamino-phenyl)-3-trifluorome...)
Affinity DataIC50:  26.9nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057528(4-[5-(4-Chloro-phenyl)-4-ethyl-3-trifluoromethyl-p...)
Affinity DataIC50:  28.2nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057561(4-[3-Benzyloxymethyl-5-(4-chloro-phenyl)-pyrazol-1...)
Affinity DataIC50:  28.8nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057518(4-(5-Phenyl-3-trifluoromethyl-pyrazol-1-yl)-benzen...)
Affinity DataIC50:  31.6nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  39.8nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057564(4-[5-(4-Fluoro-phenyl)-3-trifluoromethyl-pyrazol-1...)
Affinity DataIC50:  40.7nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057601(4-[5-(2-Chloro-phenyl)-3-trifluoromethyl-pyrazol-1...)
Affinity DataIC50:  56.2nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057546(4-[5-(2-Fluoro-phenyl)-3-trifluoromethyl-pyrazol-1...)
Affinity DataIC50:  57.5nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057606(4-[4-Chloro-5-(4-chloro-phenyl)-3-trifluoromethyl-...)
Affinity DataIC50:  64.6nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057539(4-(5-o-Tolyl-3-trifluoromethyl-pyrazol-1-yl)-benze...)
Affinity DataIC50:  69.2nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057548(4-(4-Cyano-5-p-tolyl-pyrazol-1-yl)-benzenesulfonam...)
Affinity DataIC50:  75.9nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057530(4-(4-Methoxy-5-phenyl-3-trifluoromethyl-pyrazol-1-...)
Affinity DataIC50:  79.4nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057571(4-(5-Cyclohex-1-enyl-3-trifluoromethyl-pyrazol-1-y...)
Affinity DataIC50:  83.2nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057567(4-(5-m-Tolyl-3-trifluoromethyl-pyrazol-1-yl)-benze...)
Affinity DataIC50:  110nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057525(4-[5-(2,4-Dimethyl-phenyl)-3-trifluoromethyl-pyraz...)
Affinity DataIC50:  120nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057542(4-(3-Difluoromethyl-5-phenyl-pyrazol-1-yl)-benzene...)
Affinity DataIC50:  129nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057572(4-[4-Chloro-5-(4-chloro-phenyl)-3-cyano-pyrazol-1-...)
Affinity DataIC50:  141nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057619(4-Chloro-5-(4-chloro-phenyl)-1-(4-sulfamoyl-phenyl...)
Affinity DataIC50:  158nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057555(4-[5-(2-Methoxy-phenyl)-3-trifluoromethyl-pyrazol-...)
Affinity DataIC50:  288nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057579(4-[3-Cyano-5-(4-fluoro-phenyl)-pyrazol-1-yl]-benze...)
Affinity DataIC50:  339nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057516(4-[5-(3,5-Difluoro-4-methoxy-phenyl)-3-difluoromet...)
Affinity DataIC50:  347nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057619(4-Chloro-5-(4-chloro-phenyl)-1-(4-sulfamoyl-phenyl...)
Affinity DataIC50:  407nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057607(4-[5-(3,4-Dimethoxy-phenyl)-3-trifluoromethyl-pyra...)
Affinity DataIC50:  603nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057553(4-[5-(4-Chloro-phenyl)-4-methyl-3-trifluoromethyl-...)
Affinity DataIC50:  933nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057587(4-Chloro-5-(4-chloro-phenyl)-1-(4-sulfamoyl-phenyl...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057592(4-[5-(2,3-Dihydro-benzofuran-5-yl)-3-trifluorometh...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057591(4-[5-(4-Methylsulfanyl-phenyl)-3-trifluoromethyl-p...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057589(4-[5-(4-Methoxy-phenyl)-3-trifluoromethyl-pyrazol-...)
Affinity DataIC50:  2.57E+3nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057574(4-[5-(4-Nitro-phenyl)-3-trifluoromethyl-pyrazol-1-...)
Affinity DataIC50:  2.63E+3nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057612(4-[3-Difluoromethyl-5-(5-methyl-furan-2-yl)-pyrazo...)
Affinity DataIC50:  3.31E+3nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057575(4-[5-(4-Dimethylamino-3-fluoro-phenyl)-3-trifluoro...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057605(4-[5-(5-Chloro-thiophen-2-yl)-3-trifluoromethyl-py...)
Affinity DataIC50:  4.68E+3nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057565(4-(4-Amino-5-phenyl-pyrazol-1-yl)-benzenesulfonami...)
Affinity DataIC50:  5.13E+3nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057618(4-[5-(3-Methyl-4-methylsulfanyl-phenyl)-3-trifluor...)
Affinity DataIC50:  6.31E+3nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50057587(4-Chloro-5-(4-chloro-phenyl)-1-(4-sulfamoyl-phenyl...)
Affinity DataIC50:  8.71E+3nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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