Compile Data Set for Download or QSAR
maximum 50k data
Found 9 Enz. Inhib. hit(s) with all data for entry = 50012843
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50123241((S)-2-[(3S,5R)-3-Isobutyl-5-methyl-2-oxo-4-(2-quin...)
Affinity DataIC50:  70nMAssay Description:Inhibition of LFA-1/ICAM-1 interaction in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50123239((S)-2-[(3S,5R)-3-Isobutyl-5-methyl-2-oxo-4-(2-quin...)
Affinity DataIC50:  110nMAssay Description:Inhibition of LFA-1/ICAM-1 interaction in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50123244((S)-2-((3S,5R)-3-Isobutyl-5-methyl-2-oxo-4-phenyla...)
Affinity DataIC50:  750nMAssay Description:Inhibition of LFA-1/ICAM-1 interaction in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50123237((S)-2-[(3S,5R)-3-Isobutyl-5-methyl-2-oxo-4-(2-pyri...)
Affinity DataIC50:  970nMAssay Description:Inhibition of LFA-1/ICAM-1 interaction in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50123242((S)-2-{(3S,5R)-4-[2-(4-Bromo-phenyl)-acetyl]-3-iso...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of LFA-1/ICAM-1 interaction in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50123240((S)-2-[(3S,5R)-3-Isobutyl-5-methyl-4-(2-naphthalen...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of LFA-1/ICAM-1 interaction in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50123245((S)-2-[(3S,5R)-3-Isobutyl-5-methyl-2-oxo-4-(2-quin...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of LFA-1/ICAM-1 interaction in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50123243((S)-2-[(3S,5R)-3-Isobutyl-5-methyl-4-(2-naphthalen...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of LFA-1/ICAM-1 interaction in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-L/Integrin beta-2/Intercellular adhesion molecule 1(Homo sapiens (Human))
Novartis Institute For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50123238((S)-2-[(S)-3-Isobutyl-5-methyl-4-(2-naphthalen-2-y...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of LFA-1/ICAM-1 interaction in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed