Compile Data Set for Download or QSAR
maximum 50k data
Found 18 Enz. Inhib. hit(s) with all data for entry = 50035296
TargetSphingomyelin phosphodiesterase 2(Rattus norvegicus)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50100341((2E,4E,6E,12E)-(8R,10S,14R)-8,10,12,14-Tetramethyl...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingomyelin phosphodiesterase 2(Rattus norvegicus)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50128902(CHEMBL59342 | Pyridin-4-ylmethyl-carbamic acid (E)...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingomyelin phosphodiesterase 2(Rattus norvegicus)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50128892(CHEMBL62020 | Pyridin-3-ylmethyl-carbamic acid (E)...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingomyelin phosphodiesterase 2(Rattus norvegicus)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50128891(CHEMBL261976 | Pyridin-4-ylmethyl-carbamic acid (E...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingomyelin phosphodiesterase 2(Rattus norvegicus)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50128908((2-Dimethylamino-ethyl)-carbamic acid (E)-(2S,3R)-...)
Affinity DataIC50:  4.10E+3nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingomyelin phosphodiesterase 2(Rattus norvegicus)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50128903((3-Dimethylamino-propyl)-carbamic acid (E)-(2S,3R)...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingomyelin phosphodiesterase 2(Rattus norvegicus)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50128898(CHEMBL59845 | Pyridin-2-ylmethyl-carbamic acid (E)...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingomyelin phosphodiesterase 2(Rattus norvegicus)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50128906(CHEMBL59120 | Pyridin-2-yl-carbamic acid (E)-(2S,3...)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingomyelin phosphodiesterase 2(Rattus norvegicus)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50128905((4-Dimethylamino-benzyl)-carbamic acid (E)-(2S,3R)...)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingomyelin phosphodiesterase 2(Rattus norvegicus)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50128900((2-Pyridin-2-yl-ethyl)-carbamic acid (E)-(2S,3R)-2...)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingomyelin phosphodiesterase 2(Rattus norvegicus)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50128896(CHEMBL416323 | {2-[(E)-(2S,3R)-2-(2,2-Dimethyl-pro...)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingomyelin phosphodiesterase 2(Rattus norvegicus)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50128904((2-Diisopropylamino-ethyl)-carbamic acid (E)-(2S,3...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingomyelin phosphodiesterase 2(Rattus norvegicus)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50128895(4-Dimethylamino-butyric acid (E)-(2S,3R)-2-(2,2-di...)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingomyelin phosphodiesterase 2(Rattus norvegicus)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50128897((3,3-Dimethyl-butyl)-carbamic acid (E)-(2S,3R)-2-(...)
Affinity DataIC50:  7.70E+4nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingomyelin phosphodiesterase 2(Rattus norvegicus)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50128901(CHEMBL58502 | Pyridin-4-ylmethyl-carbamic acid (E)...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingomyelin phosphodiesterase 2(Rattus norvegicus)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50128899((S)-Pyridin-4-ylmethyl-carbamic acid (R)-2-amino-3...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingomyelin phosphodiesterase 2(Rattus norvegicus)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50128907(CHEMBL59031 | Pyridin-4-ylmethyl-carbamic acid (E)...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingomyelin phosphodiesterase 2(Rattus norvegicus)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50128894(CHEMBL300328 | Pyridin-4-ylmethyl-carbamic acid (E...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed