Compile Data Set for Download or QSAR
maximum 50k data
Found 14 Enz. Inhib. hit(s) with all data for entry = 50000021
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50000334(6,7-Dichloro-1,5-dihydro-imidazo[2,1-b]quinazolin-...)
Affinity DataIC50:  82nMAssay Description:Inhibition of human blood platelet c-AMP phosphodiesteraseMore data for this Ligand-Target Pair
TargetThromboxane-A synthase(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50000308(6-(Imidazol-1-yl-phenyl-methyl)-3,4-dihydro-1H-qui...)
Affinity DataIC50:  350nMAssay Description:Compound was evaluated for the inhibition of human blood platelet,thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50000318(6-(2-Imidazol-1-yl-vinyl)-1H-quinolin-2-one | CHEM...)
Affinity DataIC50:  380nMAssay Description:Compound was evaluated for the inhibition of human blood platelet,thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50000306(6-Pyridin-3-yl-3,4-dihydro-1H-quinolin-2-one | 6-P...)
Affinity DataIC50:  540nMAssay Description:Compound was evaluated for the inhibition of human blood platelet,thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50000310(6-(2-Imidazol-1-yl-vinyl)-3,4-dihydro-1H-quinolin-...)
Affinity DataIC50:  1.20E+3nMAssay Description:Compound was evaluated for the inhibition of human blood platelet thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50000309(6-Imidazol-1-yl-3,4-dihydro-1H-quinolin-2-one | CH...)
Affinity DataIC50:  2.00E+3nMAssay Description:Compound was evaluated for the inhibition of human blood platelet,thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50000318(6-(2-Imidazol-1-yl-vinyl)-1H-quinolin-2-one | CHEM...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of human blood platelet c-AMP phosphodiesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50000306(6-Pyridin-3-yl-3,4-dihydro-1H-quinolin-2-one | 6-P...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of human blood platelet c-AMP phosphodiesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50000315((CI-914)6-(4-Imidazol-1-yl-phenyl)-4,5-dihydro-2H-...)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of human blood platelet c-AMP phosphodiesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50000310(6-(2-Imidazol-1-yl-vinyl)-3,4-dihydro-1H-quinolin-...)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of human blood platelet c-AMP phosphodiesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50000328(6-(1-Imidazol-1-ylmethyl-hexyl)-3,4-dihydro-1H-qui...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of human blood platelet c-AMP phosphodiesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50000309(6-Imidazol-1-yl-3,4-dihydro-1H-quinolin-2-one | CH...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of human blood platelet c-AMP phosphodiesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50000328(6-(1-Imidazol-1-ylmethyl-hexyl)-3,4-dihydro-1H-qui...)
Affinity DataIC50:  2.50E+4nMAssay Description:Compound was evaluated for the inhibition of human blood platelet thromboxane A2 synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Syntex Research

Curated by ChEMBL
LigandPNGBDBM50000308(6-(Imidazol-1-yl-phenyl-methyl)-3,4-dihydro-1H-qui...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of human blood platelet c-AMP phosphodiesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed