Compile Data Set for Download or QSAR
maximum 50k data
Found 17 Enz. Inhib. hit(s) with all data for entry = 50000266
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50003753(6,7-Dichloro-2-(2-pyrrolidin-1-yl-ethyl)-1,2,3,4-t...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-pentazocine in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50003748(CHEMBL342223 | [2-(3,4-Dichloro-phenyl)-ethyl]-(1-...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-pentazocine in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50003754((-)-1-[2-(3,4-Dichloro-phenyl)-ethyl]-2-pyrrolidin...)
Affinity DataKi:  1.80nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-pentazocine in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50000069(CHEMBL20377 | [2-(3,4-Dichloro-phenyl)-ethyl]-meth...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-pentazocine in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50003750(CHEMBL137348 | [2-(3,4-Dichloro-phenyl)-ethyl]-met...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-pentazocine in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50003752(1-[2-(3,4-Dichloro-phenyl)-ethyl]-3-pyrrolidin-1-y...)
Affinity DataKi:  2.70nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-pentazocine in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50035131((+)-(6R,11S)-6,11-dimethyl-3-(3-methyl-but-2-enyl)...)
Affinity DataKi:  3.10nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-pentazocine in guinea pig brain homogenatesMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50003745(1-[2-(3,4-Dichloro-phenyl)-ethyl]-3-pyrrolidin-1-y...)
Affinity DataKi:  3.60nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-pentazocine in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50003744(CHEMBL342942 | [2-(3,4-Dichloro-phenyl)-ethyl]-met...)
Affinity DataKi:  3.70nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-pentazocine in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  3.70nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-pentazocine in guinea pig brain homogenatesMore data for this Ligand-Target Pair
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50003756((+)-1-[2-(3,4-Dichloro-phenyl)-ethyl]-2-pyrrolidin...)
Affinity DataKi:  4.30nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-pentazocine in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50003743((-)-[2-(3,4-Dichloro-phenyl)-ethyl]-methyl-(2-pyrr...)
Affinity DataKi:  7.80nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-pentazocine in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50003746(CHEMBL138123 | [2-(3,4-Dichloro-phenyl)-ethyl]-(1-...)
Affinity DataKi:  16nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-pentazocine in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50003747((+)-[2-(3,4-Dichloro-phenyl)-ethyl]-methyl-(2-pyrr...)
Affinity DataKi:  19nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-pentazocine in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM81982(CAS_97-39-2 | DITOLYLGUANIDINE | DTG | Di-o-tolylg...)
Affinity DataKi:  28nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-pentazocine in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50003749((2S)-N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-2-(p...)
Affinity DataKi:  427nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-pentazocine in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Homo sapiens (Human))
National Institute Of Diabetes And Digestive And Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50003755((2R)-N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-2-(p...)
Affinity DataKi:  455nMAssay Description:Binding affinity for sigma receptor using [3H]-(+)-pentazocine in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed