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Found 13 Enz. Inhib. hit(s) with all data for entry = 50013782
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50204884(6-(2-(4-(4-fluorobenzyl)piperidin-1-yl)ethylsulfin...)
Affinity DataIC50:  8nMAssay Description:Inhibition of N-methyl-D-aspartate glutamate receptor-evoked increase of intracellular Ca+ in cells expressing NMDA glutamate receptor 1/2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50134652((4-Benzyl-piperidin-1-yl)-(4,6-dihydroxy-1H-indol-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of N-methyl-D-aspartate glutamate receptor-evoked increase of intracellular Ca+ in cells expressing NMDA glutamate receptor 1/2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50134648((6-Hydroxy-1H-indol-2-yl)-(4-phenoxymethyl-piperid...)
Affinity DataIC50:  19nMAssay Description:Inhibition of N-methyl-D-aspartate glutamate receptor-evoked increase of intracellular Ca+ in cells expressing NMDA glutamate receptor 1/2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50134651((4-Benzyl-piperidin-1-yl)-(6-hydroxy-1H-indol-2-yl...)
Affinity DataIC50:  20nMAssay Description:Inhibition of N-methyl-D-aspartate glutamate receptor-evoked increase of intracellular Ca+ in cells expressing NMDA glutamate receptor 1/2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50134649((6-Hydroxy-1H-indol-2-yl)-(4-phenethyl-piperidin-1...)
Affinity DataIC50:  24nMAssay Description:Inhibition of N-methyl-D-aspartate glutamate receptor-evoked increase of intracellular Ca+ in cells expressing NMDA glutamate receptor 1/2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50134653((4-Benzyl-piperidin-1-yl)-(4-hydroxy-1H-indol-2-yl...)
Affinity DataIC50:  39nMAssay Description:Inhibition of N-methyl-D-aspartate glutamate receptor-evoked increase of intracellular Ca+ in cells expressing NMDA glutamate receptor 1/2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50134657((4-Benzyl-piperidin-1-yl)-(5-hydroxy-1H-indol-2-yl...)
Affinity DataIC50:  40nMAssay Description:Inhibition of N-methyl-D-aspartate glutamate receptor-evoked increase of intracellular Ca+ in cells expressing NMDA glutamate receptor 1/2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50134656((4-Benzyloxy-piperidin-1-yl)-(6-hydroxy-1H-indol-2...)
Affinity DataIC50:  46nMAssay Description:Inhibition of N-methyl-D-aspartate glutamate receptor-evoked increase of intracellular Ca+ in cells expressing NMDA glutamate receptor 1/2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50134654((4-Benzyl-piperidin-1-yl)-(5,7-dihydroxy-1H-indol-...)
Affinity DataIC50:  52nMAssay Description:Inhibition of N-methyl-D-aspartate glutamate receptor-evoked increase of intracellular Ca+ in cells expressing NMDA glutamate receptor 1/2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50080029(4-((1R,2S)-3-(4-benzylpiperidin-1-yl)-1-hydroxy-2-...)
Affinity DataIC50:  57nMAssay Description:Inhibition of N-methyl-D-aspartate glutamate receptor-evoked increase of intracellular Ca+ in cells expressing NMDA glutamate receptor 1/2BMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50134650((4-Benzyl-piperidin-1-yl)-(7-hydroxy-1H-indol-2-yl...)
Affinity DataIC50:  77nMAssay Description:Inhibition of N-methyl-D-aspartate glutamate receptor-evoked increase of intracellular Ca+ in cells expressing NMDA glutamate receptor 1/2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50080016((E)-1-(4-Benzyl-piperidin-1-yl)-3-(4-hydroxy-pheny...)
Affinity DataIC50:  104nMAssay Description:Inhibition of N-methyl-D-aspartate glutamate receptor-evoked increase of intracellular Ca+ in cells expressing NMDA glutamate receptor 1/2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Homo sapiens (Human))
Gedeon Richter

Curated by ChEMBL
LigandPNGBDBM50134655((6-Hydroxy-1H-indol-2-yl)-(4-phenyl-piperidin-1-yl...)
Affinity DataIC50: >8.00E+3nMAssay Description:Inhibition of N-methyl-D-aspartate glutamate receptor-evoked increase of intracellular Ca+ in cells expressing NMDA glutamate receptor 1/2BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed