Compile Data Set for Download or QSAR
maximum 50k data
Found 44 Enz. Inhib. hit(s) with all data for entry = 50014124
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  36nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138441(2-(hydroxymethyl)-4-(5-(4-(methylthio)phenyl)-3-(t...)
Affinity DataIC50:  235nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138454(2-Hydroxymethyl-4-[5-(4-methoxy-phenyl)-3-trifluor...)
Affinity DataIC50:  365nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50452007(CHEMBL2112872)
Affinity DataIC50:  570nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138444(4-(5-(4-bromophenyl)-3-(trifluoromethyl)-1H-pyrazo...)
Affinity DataIC50:  592nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138447(4-[5-(4-Chloro-phenyl)-3-trifluoromethyl-pyrazol-1...)
Affinity DataIC50:  712nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138458(2-Hydroxymethyl-4-(5-m-tolyl-3-trifluoromethyl-pyr...)
Affinity DataIC50:  728nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138452(2-Hydroxymethyl-4-(5-p-tolyl-3-trifluoromethyl-pyr...)
Affinity DataIC50:  760nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138460(4-[5-(4-Ethoxy-phenyl)-3-trifluoromethyl-pyrazol-1...)
Affinity DataIC50:  901nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138445(4-[5-(4-Ethyl-phenyl)-3-trifluoromethyl-pyrazol-1-...)
Affinity DataIC50:  1.38E+3nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138459(4-[5-(3-Chloro-phenyl)-3-trifluoromethyl-pyrazol-1...)
Affinity DataIC50:  1.95E+3nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138442(4-[5-(4-Fluoro-phenyl)-3-trifluoromethyl-pyrazol-1...)
Affinity DataIC50:  1.99E+3nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138455(CHEMBL344540 | N-{5-[5-(4-Methoxy-phenyl)-3-triflu...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138446(CHEMBL358122 | {2-Methanesulfonyl-5-[5-(4-methoxy-...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138461(4-[5-(2-Fluoro-phenyl)-3-trifluoromethyl-pyrazol-1...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138456(2-Hydroxymethyl-4-(5-phenyl-3-trifluoromethyl-pyra...)
Affinity DataIC50:  3.45E+3nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138448(CHEMBL149781 | N-[2-Sulfamoyl-5-(5-p-tolyl-3-trifl...)
Affinity DataIC50:  4.62E+3nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 from ram seminal vesiclesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138449(CHEMBL146465 | N-{5-[5-(4-Chloro-phenyl)-3-trifluo...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138443(4-[5-(2-Chloro-phenyl)-3-trifluoromethyl-pyrazol-1...)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138448(CHEMBL149781 | N-[2-Sulfamoyl-5-(5-p-tolyl-3-trifl...)
Affinity DataIC50:  6.85E+3nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138451(4-[5-(3-Fluoro-phenyl)-3-trifluoromethyl-pyrazol-1...)
Affinity DataIC50:  7.05E+3nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  1.07E+4nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 from ram seminal vesiclesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138453(2-Hydroxymethyl-4-[5-(2-methoxy-phenyl)-3-trifluor...)
Affinity DataIC50:  2.86E+4nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50452007(CHEMBL2112872)
Affinity DataIC50:  3.46E+4nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 from ram seminal vesiclesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138457(4-[5-(4-Ethylsulfanyl-phenyl)-3-trifluoromethyl-py...)
Affinity DataIC50:  5.12E+4nMAssay Description:Inhibitory activity against human Prostaglandin G/H synthase 2 expressed in sf-9 cells infected with baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138441(2-(hydroxymethyl)-4-(5-(4-(methylthio)phenyl)-3-(t...)
Affinity DataIC50:  5.97E+4nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 from ram seminal vesiclesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138454(2-Hydroxymethyl-4-[5-(4-methoxy-phenyl)-3-trifluor...)
Affinity DataIC50:  6.30E+4nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 from ram seminal vesiclesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138455(CHEMBL344540 | N-{5-[5-(4-Methoxy-phenyl)-3-triflu...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 from ram seminal vesiclesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138449(CHEMBL146465 | N-{5-[5-(4-Chloro-phenyl)-3-trifluo...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 from ram seminal vesiclesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138460(4-[5-(4-Ethoxy-phenyl)-3-trifluoromethyl-pyrazol-1...)
Affinity DataIC50:  1.35E+5nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 from ram seminal vesiclesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138444(4-(5-(4-bromophenyl)-3-(trifluoromethyl)-1H-pyrazo...)
Affinity DataIC50:  2.30E+5nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 from ram seminal vesiclesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138452(2-Hydroxymethyl-4-(5-p-tolyl-3-trifluoromethyl-pyr...)
Affinity DataIC50:  2.78E+5nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 from ram seminal vesiclesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138457(4-[5-(4-Ethylsulfanyl-phenyl)-3-trifluoromethyl-py...)
Affinity DataIC50:  3.00E+5nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 from ram seminal vesiclesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138446(CHEMBL358122 | {2-Methanesulfonyl-5-[5-(4-methoxy-...)
Affinity DataIC50:  3.00E+5nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 from ram seminal vesiclesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138458(2-Hydroxymethyl-4-(5-m-tolyl-3-trifluoromethyl-pyr...)
Affinity DataIC50:  3.27E+5nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 from ram seminal vesiclesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138447(4-[5-(4-Chloro-phenyl)-3-trifluoromethyl-pyrazol-1...)
Affinity DataIC50:  3.36E+5nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 from ram seminal vesiclesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138459(4-[5-(3-Chloro-phenyl)-3-trifluoromethyl-pyrazol-1...)
Affinity DataIC50:  4.65E+5nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 from ram seminal vesiclesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138442(4-[5-(4-Fluoro-phenyl)-3-trifluoromethyl-pyrazol-1...)
Affinity DataIC50:  5.00E+5nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 from ram seminal vesiclesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138461(4-[5-(2-Fluoro-phenyl)-3-trifluoromethyl-pyrazol-1...)
Affinity DataIC50:  5.00E+5nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 from ram seminal vesiclesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138445(4-[5-(4-Ethyl-phenyl)-3-trifluoromethyl-pyrazol-1-...)
Affinity DataIC50:  5.00E+5nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 from ram seminal vesiclesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138443(4-[5-(2-Chloro-phenyl)-3-trifluoromethyl-pyrazol-1...)
Affinity DataIC50:  5.12E+5nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 from ram seminal vesiclesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138451(4-[5-(3-Fluoro-phenyl)-3-trifluoromethyl-pyrazol-1...)
Affinity DataIC50:  1.00E+6nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 from ram seminal vesiclesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138456(2-Hydroxymethyl-4-(5-phenyl-3-trifluoromethyl-pyra...)
Affinity DataIC50:  1.09E+6nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 from ram seminal vesiclesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Discovery Research-Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50138453(2-Hydroxymethyl-4-[5-(2-methoxy-phenyl)-3-trifluor...)
Affinity DataIC50:  1.15E+6nMAssay Description:Inhibitory activity against prostaglandin G/H synthase 1 from ram seminal vesiclesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed