Compile Data Set for Download or QSAR
maximum 50k data
Found 37 Enz. Inhib. hit(s) with all data for entry = 50014305
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140659(CHEMBL287371 | [6-(4-Ethoxy-phenyl)-4,5,7-trimethy...)
Affinity DataIC50:  40nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140656(CHEMBL26552 | [6-(4-Ethoxy-phenyl)-4,5,7-trimethyl...)
Affinity DataIC50:  75nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140645(6-(4-Ethoxy-phenyl)-1,5,7-trimethyl-4-p-tolyl-6H-p...)
Affinity DataIC50:  86nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140641(6-(4-Ethoxy-phenyl)-1-(4-ethyl-phenyl)-4,5,7-trime...)
Affinity DataIC50:  107nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140629(1-(2-Cyclopentyl-ethyl)-6-(4-ethoxy-phenyl)-4,5,7-...)
Affinity DataIC50:  148nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140664(1,6-Bis-(4-ethoxy-phenyl)-4,5,7-trimethyl-6H-pyrro...)
Affinity DataIC50:  153nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140642(6-(4-Ethoxy-phenyl)-1-(4-methoxy-phenyl)-4,5,7-tri...)
Affinity DataIC50:  154nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140631(1-Cyclopropyl-6-(4-ethoxy-phenyl)-4,5,7-trimethyl-...)
Affinity DataIC50:  170nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140632(CHEMBL24747 | [6-(4-Ethoxy-phenyl)-4,5,7-trimethyl...)
Affinity DataIC50:  170nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140662(6-(4-Ethoxy-phenyl)-1-isobutyl-4,5,7-trimethyl-6H-...)
Affinity DataIC50:  171nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140647(6-(4-Ethoxy-phenyl)-1,4,5,7-tetramethyl-6H-pyrrolo...)
Affinity DataIC50:  180nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140643(1-Cyclopentyl-6-(4-ethoxy-phenyl)-4,5,7-trimethyl-...)
Affinity DataIC50:  185nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140639(1-Cyclopentylmethyl-6-(4-ethoxy-phenyl)-4,5,7-trim...)
Affinity DataIC50:  211nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140630(1-Cyclohexyl-6-(4-ethoxy-phenyl)-4,5,7-trimethyl-6...)
Affinity DataIC50:  235nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140644(CHEMBL24700 | [6-(4-Ethoxy-phenyl)-4,5,7-trimethyl...)
Affinity DataIC50:  240nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140653(6-(4-Ethoxy-phenyl)-1-ethyl-4,5,7-trimethyl-6H-pyr...)
Affinity DataIC50:  250nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140652(6-(4-Ethoxy-phenyl)-1,5,7-trimethyl-4-(3-methyl-bu...)
Affinity DataIC50:  263nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140628(6-(4-Ethoxy-phenyl)-1-(3-methoxy-phenyl)-4,5,7-tri...)
Affinity DataIC50:  335nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140636(6-(4-Ethoxy-phenyl)-1,5,7-trimethyl-4-pentyl-6H-py...)
Affinity DataIC50:  360nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140633(6-(4-Ethoxy-phenyl)-1,5,7-trimethyl-4-phenyl-6H-py...)
Affinity DataIC50:  382nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140663(CHEMBL24225 | [6-(4-Ethoxy-phenyl)-4,5,7-trimethyl...)
Affinity DataIC50:  440nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140655(6-(4-Ethoxy-phenyl)-1-(4-fluoro-phenyl)-4,5,7-trim...)
Affinity DataIC50:  528nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140648(6-(4-Ethoxy-phenyl)-1,5,7-trimethyl-4-(2,4,4-trime...)
Affinity DataIC50:  577nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140649(1-(2,4-Dimethoxy-phenyl)-6-(4-ethoxy-phenyl)-4,5,7...)
Affinity DataIC50:  597nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140634(1-(4-Chloro-phenyl)-6-(4-ethoxy-phenyl)-4,5,7-trim...)
Affinity DataIC50:  701nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140640(6-(4-Ethoxy-phenyl)-1-(2-methoxy-phenyl)-4,5,7-tri...)
Affinity DataIC50:  737nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140654(1-Biphenyl-4-yl-6-(4-ethoxy-phenyl)-4,5,7-trimethy...)
Affinity DataIC50:  1.26E+3nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140651(1-(3-Chloro-phenyl)-6-(4-ethoxy-phenyl)-4,5,7-trim...)
Affinity DataIC50:  1.60E+3nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140650(6-(4-Ethoxy-phenyl)-1,5,7-trimethyl-4-(4-trifluoro...)
Affinity DataIC50:  1.73E+3nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140635(6-(2-Ethoxy-phenyl)-1,4,5,7-tetramethyl-6H-pyrrolo...)
Affinity DataIC50:  1.85E+3nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140658(6-(4-Ethoxy-phenyl)-1-methoxy-4,5,7-trimethyl-6H-p...)
Affinity DataIC50:  2.18E+3nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140637(1-(2-Chloro-phenyl)-6-(4-ethoxy-phenyl)-4,5,7-trim...)
Affinity DataIC50:  4.37E+3nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140657(1,4,5,7-Tetramethyl-6-(4-propoxy-phenyl)-6H-pyrrol...)
Affinity DataIC50:  5.18E+3nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140638(CHEMBL280835 | N-[6-(4-Ethoxy-phenyl)-4,5,7-trimet...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140661(6-(3-Ethoxy-phenyl)-1,4,5,7-tetramethyl-6H-pyrrolo...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140660(6-(4-Methoxy-phenyl)-1,4,5,7-tetramethyl-6H-pyrrol...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50140646(CHEMBL415465 | [6-(4-Ethoxy-phenyl)-4,5,7-trimethy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity for huamn alpha2-delta1 subunit of voltage gated calcium channel over-expressed in A710 cell membranes using [3H]-gabapentinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed