Compile Data Set for Download or QSAR
maximum 50k data
Found 34 Enz. Inhib. hit(s) with all data for entry = 50035401
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM31090((E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-eth...)
Affinity DataIC50:  80nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122578(4-Dimethylamino-but-2-ynoic acid [4-(3-bromo-pheny...)
Affinity DataIC50:  90nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122565(4-Dipropylamino-but-2-ynoic acid [4-(3-bromo-pheny...)
Affinity DataIC50:  130nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50148236(4-(2-Methoxymethyl-pyrrolidin-1-yl)-but-2-ynoic ac...)
Affinity DataIC50:  150nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122566(4-Diisopropylamino-but-2-ynoic acid [4-(3-bromo-ph...)
Affinity DataIC50:  250nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122567((E)-4-Dimethylamino-but-2-enoic acid [4-(3-bromo-p...)
Affinity DataIC50:  310nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50148234(3-Methoxymethoxy-propynoic acid [4-(3-bromo-phenyl...)
Affinity DataIC50:  330nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122577(4-Thiomorpholin-4-yl-but-2-ynoic acid [4-(3-bromo-...)
Affinity DataIC50:  550nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122579(CHEMBL117326 | N-[4-(3-Chloro-4-fluoro-phenylamino...)
Affinity DataIC50:  560nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122562(CHEMBL281300 | N-[4-(3-Bromo-phenylamino)-3-cyano-...)
Affinity DataIC50:  590nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122563((E)-4-Dimethylamino-but-2-enoic acid [4-(3-chloro-...)
Affinity DataIC50:  650nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122588(4-Methoxy-but-2-ynoic acid [4-(3-bromo-phenylamino...)
Affinity DataIC50:  790nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122560((E)-4-Dimethylamino-but-2-enoic acid [4-(3-bromo-p...)
Affinity DataIC50:  790nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122583(CHEMBL324718 | N-[4-(3-Bromo-phenylamino)-3-cyano-...)
Affinity DataIC50:  810nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122572(But-2-ynoic acid [4-(3-bromo-phenylamino)-3-cyano-...)
Affinity DataIC50:  910nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50148235(3-(2-Methoxy-ethoxy)-propynoic acid [4-(3-bromo-ph...)
Affinity DataIC50:  930nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122573(But-2-ynoic acid [4-(3-bromo-phenylamino)-3-cyano-...)
Affinity DataIC50:  940nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122582(4-Methoxy-but-2-ynoic acid [4-(3-bromo-phenylamino...)
Affinity DataIC50:  960nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122581((E)-4-Dimethylamino-but-2-enoic acid [4-(3-bromo-p...)
Affinity DataIC50:  1.60E+3nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122571((E)-But-2-enoic acid [4-(3-bromo-phenylamino)-3-cy...)
Affinity DataIC50:  1.62E+3nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122589((E)-4-Diethylamino-but-2-enoic acid [4-(3-chloro-4...)
Affinity DataIC50:  1.91E+3nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122564((E)-4-Morpholin-4-yl-but-2-enoic acid [4-(3-chloro...)
Affinity DataIC50:  2.29E+3nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122574((E)-4-Dimethylamino-but-2-enoic acid [4-(3-chloro-...)
Affinity DataIC50:  2.32E+3nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122568((E)-4-Dimethylamino-but-2-enoic acid [4-(3-chloro-...)
Affinity DataIC50:  2.64E+3nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122580(CHEMBL114392 | N-[4-(3-Chloro-4-fluoro-phenylamino...)
Affinity DataIC50:  2.70E+3nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122561((E)-4-Dimethylamino-but-2-enoic acid [4-(3-bromo-p...)
Affinity DataIC50:  2.88E+3nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122576((E)-4-Morpholin-4-yl-but-2-enoic acid [4-(3-bromo-...)
Affinity DataIC50:  3.83E+3nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122558((E)-4-Diethylamino-pent-2-enoic acid [4-(3-chloro-...)
Affinity DataIC50:  4.84E+3nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122587((E)-4-Dimethylamino-pent-2-enoic acid [4-(3-chloro...)
Affinity DataIC50:  5.22E+3nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122559((E)-4-Morpholin-4-yl-but-2-enoic acid [4-(3-bromo-...)
Affinity DataIC50:  5.39E+3nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122586((E)-But-2-enoic acid [4-(3-chloro-4-fluoro-phenyla...)
Affinity DataIC50:  7.50E+3nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122584((E)-4-Morpholin-4-yl-but-2-enoic acid [4-(3-bromo-...)
Affinity DataIC50:  1.03E+4nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122557((E)-4-Morpholin-4-yl-pent-2-enoic acid [4-(3-chlor...)
Affinity DataIC50:  1.06E+4nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Georgetown University

Curated by ChEMBL
LigandPNGBDBM50122585((E)-4-Morpholin-4-yl-but-2-enoic acid [4-(3-chloro...)
Affinity DataIC50:  1.36E+4nMAssay Description:Concentration required to inhibit autophosphorylation of cytoplasmic domain of epidermal growth factor receptor (EGFR)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed