Compile Data Set for Download or QSAR
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Found 8 Enz. Inhib. hit(s) with all data for entry = 50000357
TargetProthrombin(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50004744(CHEMBL2370453 | Hirudin analogue)
Affinity DataKi:  0.140nMAssay Description:Compound was evaluated for their ability to inhibit the alpha-thrombin-mediated hydrolysis of the fluorescent substrate Tos-Gly-Pro-Arg-AmcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50004739(CHEMBL2370455 | Hirudin analogue)
Affinity DataKi:  0.370nMAssay Description:Compound was evaluated for their ability to inhibit the alpha-thrombin-mediated hydrolysis of the fluorescent substrate Tos-Gly-Pro-Arg-AmcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50004745(CHEMBL2370450 | Hirudin analogue)
Affinity DataKi:  0.560nMAssay Description:Compound was evaluated for their ability to inhibit the alpha-thrombin-mediated hydrolysis of the fluorescent substrate Tos-Gly-Pro-Arg-AmcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50004743(Ac-(D)Phe-Pro-Arg.Pro.Gln.Ser-H~s.Asn-AspGly-Asp-P...)
Affinity DataKi:  2.80nMAssay Description:Compound was evaluated for their ability to inhibit the alpha-thrombin-mediated hydrolysis of the fluorescent substrate Tos-Gly-Pro-Arg-AmcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50004742(CHEMBL385670 | Hirudin analogue)
Affinity DataKi:  3.20nMAssay Description:Compound was evaluated for their ability to inhibit the alpha-thrombin-mediated hydrolysis of the fluorescent substrate Tos-Gly-Pro-Arg-AmcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50004741(CHEMBL427978 | Hirudin analogue)
Affinity DataKi:  3.5nMAssay Description:Compound was evaluated for their ability to inhibit the alpha-thrombin-mediated hydrolysis of the fluorescent substrate Tos-Gly-Pro-Arg-AmcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50004738(CHEMBL2370451 | Hirudin analogue)
Affinity DataKi:  3.80nMAssay Description:Compound was evaluated for their ability to inhibit the alpha-thrombin-mediated hydrolysis of the fluorescent substrate Tos-Gly-Pro-Arg-AmcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
National Research Council Of Canada

Curated by ChEMBL
LigandPNGBDBM50004740(CHEMBL2370449 | Hirudin analogue)
Affinity DataKi:  300nMAssay Description:Compound was evaluated for their ability to inhibit the alpha-thrombin-mediated hydrolysis of the fluorescent substrate Tos-Gly-Pro-Arg-AmcMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed